The Kennedy Trust is delighted to award its sixth Senior Research Fellowship to Dr Tetsuo Hasegawa Cambridge University for his project exploring the role of neuroimmune interaction in the development of arthritis and immune-driven pain. Congratulations Tetsuo! kennedytrust.org/the-kennedy-tr…

Directly selecting cell-type marker genes for single-cell clustering analyses cell.com/cell-reports-m…

I'm #hiring a PhD student! Join the Lindeboom Lab at the The Netherlands Cancer Institute on an exciting project to explore oncogenic transcription factor binding kinetics and biophysics using state-of-the-art technologies! Apply now or share this exciting opportunity! nki.nl/careers-study/…

⚡️Our July issue is live! ⚡️ 🧵1/4 This special Focus issue on #PrecisionHealth includes news, opinion, review and original research articles on critical areas and challenges that must be addressed to make precision health a global reality. nature.com/nm/volumes/30/…

Most T cells recirculate and visit many lymphoid organs, but different lymph nodes each retain unique TCR repertoires Science Advances science.org/doi/10.1126/sc…

A brief summary of Spatial VDJ is available in Nature Reviews Immunology! Thanks to all the co-authors Camilla Engblom and Kim Thrane. What a STAR team to work with! 😄 👇👇👇 nature.com/articles/s4157…

Age-related dysregulation of B cells in acute respiratory distress syndrome researchsquare.com/article/rs-475…

Wow - autoantibodies against IL-10 seen in Inflammatory Bowel Disease 🤯 Neutralizing Autoantibodies against Interleukin-10 and B cell depletion was effective to treat the disease Understanding the cause enables #personalizedmedicine in #IBD nejm.org/doi/full/10.10…

We keep ignoring CHIP (clonal hematopoiesis of indeterminate potential= mutations in our blood stem cells) even though it is no longer "indeterminate." A key marker for risk of cardiovascular events and blood cancers. It should be routinely assayed in older adults.

🚨𝐇𝐞 𝐋𝐚𝐛 job opportunity UC San Francisco 🚨: I'm hiring TWO postdocs - an experimentalist and a computational biologist. Join us to use cutting-edge single-cell and spatial technologies to unravel the mysteries of human tissues. opportunities.ucsf.edu/content/open-p…

Measuring single‐cell immune clonality to track haematological cancers - Choo - 2024 - Clinical and Translational Medicine - Wiley Online Library onlinelibrary.wiley.com/doi/full/10.10…

This Perspective from Qing Nie, Fabian Theis, Xiangmin Xu and colleagues discusses the integration of small-scale datasets with each other or with larger reference atlases, particularly in the context of single-cell approaches. nature.com/articles/s4159…

Several years ago, Jennifer Chandler from UCL Child Health Kidney Lab aimed to study glomerular cell crosstalk in a model of childhood kidney failure The result: our first single-cell study, in Journal Of Pathology. Impaired angiogenic signalling is an early driver of disease …thsocjournals.onlinelibrary.wiley.com/doi/10.1002/pa…

what a #beautiful #paper Immunity Autoantigen-specific CD4 T cells acquire an exhausted phenotype and p... sciencedirect.com/science/articl…

TRI-based Di Yu 余迪 leads a UQ News #FrazerInstUQ team building an immune cell atlas with 1000 blood samples to aid diagnosing/treating children with cancer, diabetes, lupus. It will empower tailored treatments: maximum benefit, minimum side effects. bit.ly/47erCc0

Congrats team #IFCCIR Di Yu 余迪 KelvinTuong &partners QIMR Berghofer Medical Research Institute UQ Medicine for receiving #MRFF National Critical Research Infrastructure funds for developing a comprehensive atlas of immune cells to help #children with life threatening diseases uq.edu.au/news/article/2…

Thrilled to share the great news #IFCCIR Child Health Research Centre UQ Medicine received #MRFF National Critical Research Infrastructure for developing a comprehensive atlas of immune cells to help children with life-threatening diseases QIMR Berghofer Medical Research Institute Children's Health Queensland uq.edu.au/news/article/2…

In vivo reprogramming of tumor cells into dendritic cell-like cells remodels the TME and induces tumor-specific T cell responses science.org/doi/10.1126/sc… #NBThighlight

So excited to share that our paper on the ever-elusive Langerhans cell is out now! Using a combo of in vivo models and RNAseq we have been able to identify some of the intrinsic and extrinsic signals that drive LC identity. Check it out! Clare Bennett

Embracing computational immunology - Cañete - 2024 - Immunology & Cell Biology - Wiley Online Library onlinelibrary.wiley.com/doi/full/10.11…