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Autophagy adaptors OPTN and NDP52 mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates Noboru Mizushima and colleagues embopress.org/doi/full/10.10…

Visualizing nuclear pore complex plasticity with Pan-Expansion Microscopy Kimberly J Morgan, Emma Carley, Alyssa N Coyne, Jeffrey D Rothstein, C. Patrick Lusk, Megan C King doi.org/10.1101/2024.0…

Study reveals that comb jellies can fuse into a single entity post-injury, synchronizing their muscle contractions and even merging digestive tracts. Read more in Current Biology: cell.com/current-biolog… Kei Jokura (Kei Jokura) & colleagues

📢 Announcement The Indian Biological Data Centre (#IBDC) is pleased to announce the 1st edition of Computational Biology Conference (#CBC 2025), scheduled to take place from February 19–21, 2025, in Regional Centre for Biotechnology, Faridabad, India. Rajesh Gokhale Department of Biotechnology

Types of Variables

It was an amazing experience to attend and present my work at ASCB| EMBO Cell Bio 24, in San Diego. Thanks EMBO American Society for Cell Biology for the opportunity and support!

another preprint to end 2024! Wondered how synaptic vesicles are recycled in human brains? and whether you can use human brain tissues to address it? You bet! We used live human brain slices and demonstrated that ultrafast endocytosis does it!! biorxiv.org/content/10.110…

The Genome India Project offers us 10,000 genomes that represent the 4 broad linguistic groups, and regions across India incl tribal populations. They are available at the Indian Biological Data Centre at RCB, Faridabad for academics to analyze and unveil mysteries held in them.

How are cells in living tissues different from those in a dish? This question has puzzled scientists for decades. In our new preprint, we studied C. elegans roundworms to uncover how cells maintain unique internal environments. The results surprised us. biorxiv.org/content/10.110…

1/ 🧵 No, you do not always need Single-Cell RNA-seq. Single-cell RNA-seq is popular and powerful, but it's not always the best choice. Here's why you should think carefully before diving in.

If you really want to help the research in India, please scrap PMRF. It is creating inequality in the labs for the same work. Even trained postdocs are earning less than the PMRFs, who are untrained student... how can this be justified!! timesnownews.com/education/pm-r…

A groundbreaking study published in Nature (Jan 2025) significantly expanded our understanding of GBM-neural circuit interaction. Sun et al. demonstrate that GBM integrates more extensively and rapidly into neural circuits than previously understood, making GBM not only a

The Golgi Rim is a Precise Tetraplex of Golgin Proteins that Can Self-Assemble into Filamentous Bands biorxiv.org/content/10.110…

David Liu receives Breakthrough Prize in Life Sciences. David R. Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine. Breakthrough broadinstitute.org/news/david-liu…

🎓 Fully Funded PhD in Cancer Immunotherapy 🇬🇧 Fully funded PhD at the Institute of Cancer Research, London: Study the immunopeptidome of multiple myeloma to advance cancer immunotherapy. 📅 Deadline: 16 May 2025 🔗 Apply: icr.ac.uk/study-and-care…

There are so many weird Biology quirks that I somehow missed before and am only just finding now... Apparently translation can and *does* initiate from EVERY codon With the caveat that any codon other than the canonical AUG / GUG / UUG options induce transcription at such

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!

A baby named KJ, who was born with a rare genetic disorder – CPS1 deficiency – is healed thanks to doctors at the Children's Hospital who administered the world’s first personalized gene-editing treatment. The research team used base editing, a gene-editing method invented by HHMI

Excited to share Quetzal, a simple but scalable model for building 3D molecules atom-by-atom. 🐉 Named after Quetzalcoatl, the Aztec god of creation We equip a standard causal transformer with a per-atom diffusion MLP to model the continuous 3D position of the next atom. [1/3]

Plasmid-based reporter assays are the bedrock of regulatory genomics. But a basic question has gone unanswered for decades: Do chromatin architectures form on plasmids transfected into mammalian cells—and does it matter? We finally have answers. biorxiv.org/content/10.110…