PhD opportunity! Emmanuel Soubies and I are looking for a coder/cell biologist student funded by CNRS 🌍. Let's develop the FlexSIM software for better speed and quality, and apply it to the dynamics of the axonal cytoskeleton. July 3rd deadline, all info ➡️ neurocytolab.org/up/Annonce_PhD…

Version 1.0 of tif2blender is online! This includes lots of new features 🥳🔬 To use this, see the brand-new youtube tutorials! These take you from installing, to loading to presentation-ready video for fluorescence and electron microscopy! youtube.com/playlist?list=…

What an honor and a career highlight to finally be able to say: "Hey momma, won't you look at me? I'm on the cover of the J-C-B!" Congratulations to Bruno and the rest of the team on an outstanding job! Article: hubs.la/Q02zsMjC0 Spotlight: hubs.la/Q02zsLrC0

One of the most interesting things when working with game engine technology is spatial indexing algorithms. This means, ability to store 2D or 3D objects in space and query them efficiently without having to test every single of them. Here is a list of most common ones! 🧵👇

As a father, my heart is breaking looking at the pictures of russian strike at the biggest children's hospital in Ukraine. I cannot envision any humanly acceptable reason for that, apart from a pure terror. If you wanna help, here are money transfer details

Nobody is topping this thread in 2024. Come for the mammoth DNA, stay for the bangin’ music video they made about driving over beef jerky in a car 🥩 🚗 👏 👏 👏

They're finally online! The co-submitted papers finally see the light in their final form. Many thanks to Kendra Liu and Dr. Sarah Kucenas for the coordination, and Ondine Cleaver 🇺🇦 for being an excellent EIC #DevBio #zebrafish sciencedirect.com/science/articl… sciencedirect.com/science/articl…

Active nematic pumps. Microfluidic pumping driven by molecular motors! arxiv.org/html/2407.0996…

I think scientists overvalue GUIs in scientific code. A GUI doubles the amount of work you need to do, and I've never seen anyone exercise the discipline necessary to keep their algorithms separate from the GUI logic.

Kyle Douglass Recommended read in this context: User friendly GUIs, making scientific software broadly applicable, cause substantial efforts on maintenance and support side. Great alternative: Develop plugins for existing platforms. Florian Levet et al (Fig lic. CC-BY) f1000research.com/articles/10-302

How to uncoil a spring #BigTrace

Here's a work of love for #FluorescenceFriday and for your summer reading! Preprinting a new review from Ciarán Butler-Hallissey and me. It's about super-resolution microscopy of the neuronal cytoskeleton, and it has some nice images, published and unpublished 🫶 zenodo.org/records/131713…

"you can't debug print shaders" oh yeah? well check this shit out that's right, a whole ass view matrix, served directly from the GPU

I like straightforward comparison of super-resolution techniques on well-chosen biological samples! Here's one with dense little bacteria clusters: biorxiv.org/content/10.110…

In a new study, Korsten et al. from the Kapitein group Utrecht University (hubs.la/Q02LW6CL0) discovered that protein aggregates associated with Huntington’s disease poke holes in the nuclear membrane and hinder its repair. More from Genetic Engineering & Biotechnology News: hubs.la/Q02LWnYj0

The big one is out 🎉 So over the moon to see our latest work with Steph Vassilopoulos published in Science Magazine. Check out how we reveal the unique architecture of clathrin-coated pits and endocytosis at the axon initial segment: science.org/doi/10.1126/sc…

Anna Akhmanova and myself wrote a comment for Current Biology about this publication. We put it back into the context of previous works, summarized the most convincing parts and pointed at exciting questions about MT dynamics and cell migration. authors.elsevier.com/a/1jYNi3QW8S6F…

How to uncoil a snake #BigTrace

This finally convinced me to start working on a personal website! hinderling.github.io I have no idea what I'm doing, feedback welcome haha

📡🧵 Excited to release our preprint: Ultrack: Pushing the Limits of Cell Tracking Across Biological Scales doi.org/10.1101/2024.0… A tour-de-force by Jordão Bragantini, #Ultrack is a versatile, highly accurate, and fast ILP-based cell tracking software for 2D, 3D, and multicolor