Festive journal pub! Fascinating selection from the lab.

Very excited to share my first 1st-author paper which is out today, (open access!) here: nature.com/articles/s4146… Eternal thanks to Hayley Sharpe and Janet Deane's Lab for their amazing supervision and help throughout. The following thread summarises our key findings! (1/8)

Hayley Sharpe Hayley Sharpe receives a 2020 Lister Research Prize Fellowship, recognising outstanding performance and potential in biomedical research. Congratulations Hayley! The funding will help develop a new area of research #phosphatases #signalling ow.ly/isPQ50AVglm

Check out our latest 'Cell scientist to watch' interview with Hayley Sharpe Hayley Sharpe Babraham Institute : jcs.biologists.org/content/133/22…

Wishing all our followers a wonderful festive time and happy holidays. Our card showcases the winning entry to our 2020 Image Prize showing Katie Young's image of mouse organoids Hayley Sharpe. Browse more stunning research images here: babraham.ac.uk/about-us/impac…

My first review was published today! It's on protein tyrosine phosphatases in cell adhesion... portlandpress.com/biochemj/artic… Thanks to Hayley Sharpe for all the help and support

Find out more about 'Protein tyrosine phosphatases in cell adhesion' in our new review article ow.ly/6rqC50DZ4e0 #CellMigration #proteomics

Very proud of Callum Talbot-Cooper for his first first author paper!! 😀

New paper out Molecular Cell ! 🎉 Check out our study on how MYC-driven #lymphoma hacks protein translation with the little help from #DDX3X and #DDX3Y RNA helicases. sciencedirect.com/science/articl…

Congratulations Callum Talbot-Cooper , what an achievement!! 🤩 Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling cell.com/cell-host-micr…

BLOG: PhD student Tiffany shares her placement experience learning a new technique to bring back to the Institute to understand more about wound healing and skin repair Read more: babraham.ac.uk/blog/learning-… #CellSignalling #PhDLife

Preprint alert! Another wonderful collaboration with Janet Deane's Lab The CIMR led by Iain Hay. Here we characterise the phosphorylation-independent recruitment of a substrate to a protein tyrosine phosphatase via a distal domain. #phosphatases (Martha Cyert it will be a thing!).

Please RT. PhD students funded by UK Research and Innovation face a cash crisis. They are working full-time, yet earning less than living wage. With the rising cost of living and increasing pressure to deliver high quality research that benefits society, something needs to change. THREAD (1/10)

Why bother keeping an inactive enzymatic domain? Read the updated version of our preprint, now published eLife - the journal! We show that the pseudophosphatase (D2) domain of the receptor PTPRK controls substrate recruitment and specificity...🧵 elifesciences.org/articles/79855

Congratulations to our very own Katie M! 🎉 Well deserved for her excellent presentation! #SharpeTeam 🌻🌻

ONE WEEK LEFT The Sharpe lab is looking for a postdoc or research assistant to help investigate how a specific mutation in the immune phosphatase CD45 affects its function in adaptive and innate immune responses Full details: babrahaminstitute.livevacancies.co.uk/#/job/details/… #ScienceJobs Hayley Sharpe

Going to miss these guys! Oishee_Rahman Roksana Dutkiewicz @katemulholland4 (and Tiff and Kasia) Hayley Sharpe #flossphatases

Matching Bio-Rad Laboratories tattoos for some of the Sharpe lab 🌈😂 Summoning more beautiful Western Blots for 2023✨💁🏽‍♀️

Katherine Young Katie Young, Hayley Sharpe Hayley Sharpe Babraham Institute and colleagues discover that PTPRK promotes intestinal repair and catalysis-independent tumour suppression. Highlight: journals.biologists.com/jcs/article/13… Article: journals.biologists.com/jcs/article/13…

We're recruiting! Please spread the word. We're excited for someone to join our team with an interest in biochemistry and/or cell biology. The project will focus on cellular redox reactions that locally activate switches in protein complexes to drive signalling.