
Jose L. Avalos
@javaloslab
Scientist at Princeton interested in life sciences applied to human health, energy, and the environment
ID: 976686217583476736
22-03-2018 05:05:14
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Molecular tools that can switch on and off with light. Jose L. Avalos jared toettcher and team have developed a class of light-switchable "OptoBinders" to control cellular processes. One potential application includes improved production of biofuels. acee.princeton.edu/acee-news/new-…

Our optical monobody (OptoMB) showing > 300-fold reversible change in binding affinity to is membrane bound target depending on light conditions. Works in vitro and inside living cells. Done in collaboration with Jared jared toettcher Great job Cesar, Agi, Evan! nature.com/articles/s4146…

Researchers at University of Washington have designed inhibitors that block the interaction between #SARSCoV2 and human cell receptor ACE2, paving the way for therapeutics that could be delivered more easily than antibodies. fcld.ly/rp1ll80







I am very grateful to the DOE (DOE Office of Science) as well as Project-X from Princeton SEAS (Princeton Engineering), which supported us for the preliminary data -- Thank you!!


Congratulations to our own new HHMI Gilliam Fellow (Lisset Duran), with Daniel J. Cohen (CohenLab at Princeton) . Many great things to come Lisset!!

Awesome endorsement Jared (jared toettcher). Thank you so much!

Congratulations to all awardees, especially our own José Montaño and Shannon Hoffman. Great job!!

Congratulations Lisset Lisset Duran !!

I am delighted to share this review on the role of physiology in microbial metabolic engineering. It was a great experience writing it with José Montaño and Lisset Duran. Thanks also to the editors Nature Reviews Microbiology.

Our paper on isobutanol/isopentanol biosensor in yeast is finally out: nature.com/articles/s4146…. No longer screening in the dark for strains to produce these biofuels. Kudos to Yanfei Zhang Jeremy D. Cortez, Sarah Hammer, Cesar Lopez, Sergio Garcia-Echauri for their awesome work.

Proud to share a preprint describing the optoPlateReader (oPR), a device for optogenetics, spectroscopy, and feedback control in *each well* of a 96-well plate. Tremendous effort by our ugrad iGEM Headquarters team. Led by Saachi Datta and team mentor Will Benman. 👇 biorxiv.org/content/10.110…


This is a rigorous quantitative study on how to design and functionalize protein condensates to make synthetic organelles for biotechnological applications. Congratulations Mack (Mack Walls)!! Your tour de force studies are paying off!