Excited to share my thesis work in the Tsourkas lab out now in PNASNews ow.ly/2v5450wLcKR We developed a method to efficiently deliver off-the-shelf antibodies into the cytosol of cells by complexing them with cationic lipids originally developed for nucleic acid delivery.

The incredible scale of commercial production. 120L-scale E. coli cultures to get the plasmids plasmids, 2-day long restriction enzyme digests, 1L bottles of linearized DNA that undergo in vitro transcription, and so on...

Types of Scientific Paper xkcd.com/2456

Great summary of some of the amazing work from Jason Chin at the MRC completely reengineering the Ecoli genome in order to free up 3(!) sense codons for noncanonical amino acid incorpation. nejm.org/doi/full/10.10…