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📑 A natural language processing algorithm accurately classifies steatotic liver disease pathology to estimate the risk of #cirrhosis❕ #NLP #LiverTwitter #LiverX

journals.lww.com/hepcomm/fullte…

📑 Home exercise ➕branched-chain amino acids ➕ probiotics improve frailty in #cirrhosis‼️ 🌟 Patients randomized to exercise + BCAA + probiotics had ⬇️ in liver #frailty index, ⬇️ falls, and ⬇️ ER visits 🏥 ❕ journals.lww.com/hepcomm/fullte…

📑 mARC1 in MASLD: Modulation of lipid accumulation in human hepatocytes and adipocytes journals.lww.com/hepcomm/fullte…

📑 Velacur ACE outperforms FibroScan CAP for diagnosis of #MASLD‼️ 🔹Velacur ACE performed better than FibroScan CAP for #steatosis detection❕ 🔹Similar performance for fibrosis assessment #LiverTwitter #OpenAccess #NonInvasiveTesting journals.lww.com/hepcomm/fullte…

📑 Modulation of canonical Wnt signaling regulates peribiliary mesenchymal identity during homeostasis and injury❕ #LiverTwitter #OpenAccess journals.lww.com/hepcomm/fullte…

📑 The role of sinusoidal endothelial cells and TIMP1 in the regulation of fibrosis in a novel human liver 3D NASH model #LiverTwitter #MASH #OpenAccess journals.lww.com/hepcomm/fullte…

📑 Impact of pain in patients with #cirrhosis?  Big‼️      1️⃣ 1/3 of pts have pain at time of  🩺 visit despite ⬆️ rates of analgesic 💊 use  2️⃣ >75% of pain is mod/sev, often in abdomen  3️⃣ Mod-sev pain associated w ⬆️ 🏥 use and ⬆️ mortality journals.lww.com/hepcomm/fullte…

📑 Hepatitis delta testing trends in a US national cohort❗️ 🦠 New study reveals low #HepatitisDelta testing rates in US Veterans, highlighting regional disparities & the need for improved screening strategies! #LiverTwitter #OpenAccess Binu John journals.lww.com/hepcomm/fullte…

📑 GATA4 downregulation enhances CCL20-mediated immunosuppression in #HCC❗️ ⭐️ GATA4-low tumors promote immunosuppression via CCL20-driven enrichment of Tregs and MDSCs❕ journals.lww.com/hepcomm/fullte…

📑 Medication burden and anticholinergic use are associated with overt #HE in individuals with #cirrhosis❕ ⬆️Medication 💊 burden and anticholinergic exposure ⬆️ risk for HE 🧠hospitalizations❗️ journals.lww.com/hepcomm/fullte…

It was an absolute delight to contribute to this high-impact work with Tom Marjot Matthew Armstrong 💙 in which we review all things #MASLD and #Muscle related! If you're looking for holiday weekend reading, look no further: journals.lww.com/hepcomm/pages/… Hepatology Communications Elliot Tapper

This Hepatology Communications paper reviews the prevalence and impact of multi-drug resistant organisms in #cirrhosis Referenced here at APEH by Angelo Mattos and cited 15 times last year

📢Great to write this Hepatology Communications review with Matthew Armstrong 💙 & Jonathan G. Stine, MD MSc, FACP 💪We've covered everything you need to know about #Muscle & #MASLD - Insulin resistance - Sarcopenia - Myosteatosis - Impact of weight loss drugs - Benefits of exercise 🔗shorturl.at/aFO1Q

🚨 Hot off the press! Our study is the first to define meaningful score differences (MSDs) for PROMIS, CLDQ & SF-36 in CLD - key to making PROMs clinically actionable! 🔗 journals.lww.com/hepcomm/fullte… Archita Desai Eric S Orman MD MSCR Lauren Nephew MD, MSCE Naga Chalasani Indiana University Gastroenterology and Hepatology Indiana University Internal Medicine

If AFP level was 1-3 the last few times it was measured, & then "jumps" to 9, this should be a *POSITIVE* screening test for HCC (even if 9 is not above threshold): 👉Serial AFPs improve HCC screening sensitivity compared to fixed threshold journals.lww.com/hepcomm/fullte…

✅ out this month’s issue‼️ Learn about:  📑 Role of muscle in MASLD❓ 📑 Optimal AFP cut-off in HCC screening in cured HCV?❓ 📑 Min meaningful diff in PROs in cirrhosis❓ 📑 How well are we treating itch in PSC❓ 📑 How best to 🔍 fibrosis in MetALD❓ journals.lww.com/hepcomm/pages/…

📑 Serum levels of HBcAb and HBc–related Ag at the time of nucleos(t)ide analog cessation and risk of severe flares in patients with chronic #HBV 🦠 journals.lww.com/hepcomm/fullte…

📑 Duodenal-jejunal bypass ameliorates MASLD in 🐁 by regulating gut microbiota and bile acid metabolism through FXR pathways‼️ journals.lww.com/hepcomm/fullte…

📑 Hydrogen peroxide damage to 🐁 liver sinusoidal endothelial cells is prevented by n-acetyl-cysteine but not GSH❕ journals.lww.com/hepcomm/fullte…