Last month, BBC reported that GOSH, a research hospital in the UK, base edited the genome of a 12-year-old girl, Alyssa, suffering from leukemia. She had failed dozens of therapies and had no more options. Seven months later, she is cancer- free. Not many investors know about it.

My wife called and asked me to get the chicken thighs out of the freezer. I told her we don’t have any chicken thighs in the freezer so she said she’d check when she gets home- your thoughts and prayers are appreciated

Hey Apple. How about a mouse you can recharge while still using it? You know, like those wired ones you used to make…

I want a Gmail feature that automatically Bcc’s recipients when I write « moving you to bcc ».

Now can we hire the FDIC people to run California DMV? Blown away by their brutal efficiency and speed. I didn’t know that government entities could be so high performing.

which was your favorite once-in-a-generation/decade crisis - the one of 2020, 2021, 2022, or 2023?

Recruiting for Partner or Managing Director for established early stage (Seed + A) Enterprise VC in the Bay. $2b+ aum, always top quartile funds. Warm intros preferred if we don't already know each other.

Recruiting for biotech investors for tier 1 VC funds in SF and NYC, from associate to jr. partner level. Ping me for details.

Hey @jason - I used to consult for pharma companies. The key point about pharma advertising is they don’t spend to impact customers who watch news. It’s to impact the news itself. Pharma sees ad spending as part of their lobbying and public affairs budget. It is a way to buy

This pic from a pediatrics office sums up why there is growing distrust of vaccines. In the same office where doctors are saying it is "dangerous" to ask a question about a pharma product, they are serving this poison that is leading to 30% of kids to have pre-diabetes. We are

one of the easiest policy wins i can imagine for the US is to reform high-skill immigration. the fact that many of the most talented people in the world want to be here is a hard-won gift; embracing them is the key to keeping it that way. hard to get this back if we lose it.

Recruiting for investment associates & principals for a few amazing biotech-focused VC's + crossover funds in SF, NYC, LA. Open to wide variety of backgrounds. Spectacular academic achievements required. Bonus points for computational bio ML experience. PM me

Who in my network invests in the creator economy? Friend looking for seed funding for AI startup that bridges gap between brands, creators, and their audience. Superstar founders worked as leaders at Meta, Google, and YouTube. PM me for deck or intro.

Recruiting 2 Principals in SF for high profile Deep Tech VC #1 focused on space, robotics, nuclear, defense. Great backgrounds: hardware engineer @ SpaceX, Tesla, Anduril, SparkCognition, NVIDIA, etc. #2 focused on comp bio. AI x life sciences ops/BD background preferred DM me

Strong signal: VC quits their job to join a portfolio company

Recruiting up to 6 investors from associate to principal level for brand name VC funds in SF. Focus on Seed & Series A Enterprise AI. Preference for CS degrees but open to wide variety of backgrounds. DM me!

1/ Tech time machine 2020 → 2030 2/ 2020: Roll up 12 DTC brands. Get cooked by exploding Facebook ad costs. 2025: Roll up 12 accounting firms. Replace 90% of the staff with AI agents. Lose all your clients. 2030: Roll up 12 humanoid robot startups. Go bankrupt, but monetize

50%+ of VC dollars are going to AI companies. But, as folks like Alex Konrad have noted, AI tools are also rapidly changing how VC firms operate. We couldn’t find a comprehensive resource here, so we decided to write it. 📚 I’m excited to announce the launch of one of my

Before you all disappear for the Holidays (is it too late already?), here are V associate-level roles we are currently looking to fill in SF and LA, for both emerging and very established firms: 1) Deep Tech* VC Associate, SF. Q1 or Q2 start. CS or eng. degree + 1-4 yrs of MBB

🍓🍓🍓 I get the shock. The demos feel unreal because the interface between imagination and execution just collapsed. But here’s the correction most people are missing: What broke wasn’t physics. What broke was latency. We didn’t compress 200 years of discovery into six months. We