"Recent advances in laboratory automation and digitization require a teaching strategy for undergraduate students" - that is well said indeed!! Great initiative, Reinout Meijboom !

We're recruiting: vacancies.diamond.ac.uk/vacancy/postdo…. Join vast int'l collab to drive new antivirals, create big high-quality open datasets, and push new methods. Focus is crystallography, but also programming/medchem/biochem. ASAP Discovery XChem Diamond Light Source COVID Moonshot

Don't forget to use the fragment hits generated at XChem !!

Incentives are key, but public procurement was the standout incentive during the pandemic rather than #intellectualproperty. This opens the potential for non-patent incentives & #openscience in advance of the next health crisis: rdcu.be/cW6ql

The first Antiviral Drug Discovery Open Science Forum will be Wed 19 Oct 2022 at 8.00A PT / 11.00A ET! 💊 Join us to hear Frank von Delft (Frank von Delft) and James Fraser (James Fraser (A$AP J)) present SARS-CoV-2 hits discovered via X-ray fragment screening! 🚀 openantivirals.org

A historic failure

The recording of the first Antiviral Drug Discovery (AViDD) Open Science Forum is up! 🎥 Check out talks and links to data from Frank von Delft (Frank von Delft) and James Fraser (James Fraser (A$AP J)) on SARS-CoV-2 hits discovered via X-ray fragment screening! 🚀 openantivirals.org

Still can't believe we got this far, and that it's still going strong.

We are proud to be a part of the ASAP <asapdiscovery.org> Discovery team and do our best to pursue the development of new antivirals for future pandemics, (ASAP Discovery). Many thanks to John John Chodera (he/him) and the team for organizing this important meeting!

for those wanting a rapid 2min overview to Diamond Diamond Light Source ... here you go following the visit of Secretary of State Michelle Donelan yesterday - fantastic news for UK science and indeed the global science community!

Yes, this is exactly as big a deal as it sounds. And it includes cranking up XChem by another few gears - SERIOUSLY cool that it's we that get to do it!

They've asked us to convince them that XChem fragments can also help - yess! ndm.ox.ac.uk/news/ndm-resea…

Today's session is on algorithmic ways of doing what we noticed (again) in the COVID Moonshot to be an apparently effective way to progress fragment hits. 4-5:30 UK time.

We hiring two posts to XChem and ASAP Discovery, to develop next-gen methods in progressing fragment hits to potency, fast: * much smarter biophysics (vacancies.diamond.ac.uk/vacancy/postdo… - closing THIS SUNDAY); * much better informatics (vacancies.diamond.ac.uk/vacancy/pdra-o… - closing Oct 22)

Massive push from XChem, spear-headed by Daren Fearon. >10% from COVID Moonshot 😊

This is a fantastic article by Cassandra Willyard on the COVID Moonshot and how open science can help achieve global equitable and affordable access to antiviral drugs: technologyreview.com/2023/11/10/108…

Now, will they also open their wallets, he mused idly.  Real estate bubbles and weapons are after all rather more important to humanity.

Very very exciting to be part of this...