Felix Bäuerlein
@felixbauerlein
M.D. | Physicist | Dr. rer. nat. | Investigating Tissue and Neurodegeneration by #CryoET, PostDoc @uniGoettingen, previous @MPI_Biochem
ID: 55686162
https://neuropathologie.umg.eu/ueber-uns/team/ 10-07-2009 22:41:28
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If you want to literally play with a microscope, try our new LEGO based one: biorxiv.org/content/10.110…. Plans and multi-language guides to teach kids are on GitHub: github.com/tobetz/LegoMic…. Sub-micron resolution thanks to a smartphone lens. Please RT, so that it reaches the kids!
Been working with Phospho animation on amyloid aggregation. 1st effort is pretty stunning, I think! This is an in vitro, wild-type hIAPP fibril from Rodrigo Gallardo RadfordLab lovely paper in NatureStructMolBiol @Astbury_BSL Understanding Life in Molecular Detail #LoveTheWigglyBits rdcu.be/b7bGc
We have updated our joint preprint with Ruben Fernandez on #lysosome defects caused by protein aggregation, and added new data on the mechanism: Amyloid-like aggregates cause lysosomal defects in neurons via gain-of-function toxicity biorxiv.org/content/10.110…
25 years ago I was measuring whales stranded dead along Sardinian coast, or releasing back to sea those found alive. Now our cryo-EM paper on the cetacean morbillivirus nucleoprotein-RNA complex is out on Journal of Structural Biology sciencedirect.com/science/articl…
Do you wonder about the future potential of #cryoET? Will #AlphaFold replace experimental methods in structural biology or complement them? In our new review with Wolfgang Baumeister we discuss these questions in the Special Issue “AlphaFold” Journal of Molecular Biology. doi.org/10.1016/j.jmb.…
Congratulations to Wolfgang Baumeister for receiving the Alexander Hollaender Award in Biophysics 2022. ➡️nasonline.org/news-and-multi… ➡️nasonline.org/programs/award… #CryoEM #NASaward National Academy of Sciences
What an honor to receive a Consolidator grant from European Research Council (ERC) !! We are excited to dive into nervous tissues using #cryoET in our #cryoNERVE project 🤩 Thanks to everyone who made this possible!
We're hiring! We're looking for an Image Analysis Specialist to develop methods for cryo-ET data mining 🖥️ The position can become permanent upon successful evaluation. Come join us Uni Göttingen Universitätsmedizin Göttingen (UMG)! #teamtomo #cryoEM umg.eu/karriere/stell…
What is the optimal thickness of a Cryo-FIB lamellae? We quantify the tradeoff between specimen thickness and FIB damage by subtomogram averaging. There is no need to go ultra thin. Work by M Tuijtel, B Turonova Jan Philipp Kreysing Sonja Welsch Hummer Lab now online. Max Planck Institute of Biophysics #teamtomo