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Fully funded Bioinformatician position (Jr or Sr) in our team @UCPH_reNEW! Join us and delve deep into the fascinating world of developmental multi-omics. Deadline: 6/6/22; all nationalities welcome to apply. #Bioinformatics #Diversity Plz share.👇 bit.ly/3M1bbV8

In this episode we caught up with Jan Żylicz from @UCPH_reNEW to talk about his work on #epigenetic and metabolic regulation of early development. #podcast #chromatin Tune In here: bit.ly/Jan_Zylicz

Great work from @ina_huppertz and HentzeTeam highlighting, in a nutshell, how metabolism is not boring ;) Glad to have contributed with Kiran Raosaheb Patil

Fully funded PostDoc position in our team @UCPH_reNEW! Join us and delve deep into the fascinating world of human development. Deadline: October 7th; all nationalities welcome to apply. #Diversity #StemCell #postdocjobs Plz share.👇 bit.ly/3PMg6KF

📣🎉Research alert! Kiran Raosaheb Patil's group and collaborators have found that cells build a local supply chain of metabolites in the nucleus. This safeguards the supply of key factors for regulating gene expression! Read more: mrc-tox.cam.ac.uk/news/cells-bui… #Metabolism #ResearchPaper

Parts of TCA cycle function in the nucleus. Ensuring local supply of critical goods is as important for a cell as for a society. Thanks to all coauthors, especially to Eleni Kafkia for amazing effort and perseverance!

Kathryn Lilley Eleni Kafkia @filipa_bpereira Beck Laboratory Christophe Lancrin Cat Franco Paula Jouhten James Thaventhiran Judith Zaugg MRC Toxicology Unit EMBL Heidelberg Marc Zacher PTM-LOPIT is a cool technique! Nucleus seems to be one of the succinylation hot-spots; activity of corresponding metabolic enzymes in the nucleus suggests local supply, no need to transport the substrate from elsewhere

Scientists have discovered that large sections of TCA cycle, a pathway that generates energy and epigenetic modification factors in mitochondria, also operate in the nucleus. The findings change and challenge our understanding of how gene expression is regulated.

Predicting evolution with mathematical models opens opportunities for #ecology #biotech #synbio #biosustainability We demonstrate how desired but costly traits can be predictively enhanced through adaptive evolution. Fantastic team work! 1/2

Designing the metabolic environment for targeted adaptive evolution! Many congratulations @filipa_bpereira Dimitrios_Konstantinidis Paula Jouhten Kiran Raosaheb Patil and all coauthors!

#Bricklicz

Highly recommended :)

Join us :)

Metabolites & signalling functions in the context of embryo development? Fructose 1,6-biphosphate affects mesoderm patterning whilst modulating subcellular protein localization. Very happy to have contributed in the beautiful work of Hidenobu Miyazawa with Kiran Raosaheb Patil

Are you interested in how transcription targets silencing in mammals? Have a look at our new review from Nikolaos Stamidis in The EMBO Journal. reNEW #chromatin #transcription #repeats bit.ly/3xXzIFb

>13 billion #COVID19 #vaccines have been administered globally; it is thus important to study holistic effects. Our longitudinal tracking suggests minimal, if any, impact on the gut microbiome. 🙏🏽 James Thaventhiran MRC Toxicology Unit biorxiv.org/content/10.110…

Cooperative metabolic dividend enables survival of otherwise unfit species in nutrient poor media & supports diversity. + Much more in our latest preprint on synthetic gut bacterial communities in defined media 🙏🏽🙏🏽 amazing co-authors Naomi Iris van den Berg - find me on Bluesky Bork Group at EMBL Heidelberg moved to BlueSky Typas Lab et al.