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Co-evolution of immunity and seasonal influenza viruses Russell & colleagues explore the interplay between immunity evolution from previous infections or vaccination and the evolution of seasonal influenza viruses.

We recently discovered lateral transduction (LT). Now, we unveil the 4th mechanism of transduction: lateral cotransduction. This system involves SaPIs and is more powerful and versatile than phage-mediated LT. Great fun with JChen Lab and Ross Fitzgerald cell.com/cell/fulltext/…

I think we need to talk about how devastating this cancer microbiome refutation paper from Steven Salzberg 💙💛 and colleagues is. It really speaks to how devoid of critical thinking and intellectual depth our glam publishing ecosystem has become. 1/n biorxiv.org/content/10.110…

First of its kind study, shows chronic shedding of alpha variants of SARS-CoV-2 in wastewater, possibly indicating long term infections in population. medrxiv.org/content/10.110…

Mathematical modelling can be a very powerful tool to predict antimicrobial resistance dynamics. Check out our new review, led by the fantastic Christopher Witzany

For those interested in COVID-19 surveillance, our commentary is out in Health Security: “Boosting” Surveillance for a More Impactful Public Health Response During Protracted and Evolving Infectious Disease Threats: Insights From the COVID-19 Pandemic. liebertpub.com/doi/10.1089/hs…

Are you interested in synthetic engineering of phages or the interactions between phages and the immune system in the gut? Check out these two competitive PhD opportunities with me and Mike Brockhurst, Patrick Cai or Kat Coyte at The University of Manchester: bmh.manchester.ac.uk/study/research…

Our op-ed in STAT News makes a case for wastewater surveillance in facilities that can differentiate animal spread of H5N1 from spillover of H5N1 into humans. This approach would complement community-based wastewater surveillance but add a layer of opportunity for early warning.

I am speaking at ASV 2024. Please check out my talk if you're attending the event! - via #Whova event app

Some of us in NYC are preparing for the worst case scenario. Let's hope it doesn't come to that! nytimes.com/2024/06/25/nyr…

We have an opening for a PhD student in my group. Project: Understanding the mechanisms of synergistic coevolution. Approach: Coculture experiments, microscopy, analyses of fitness/ mutational effects. Deadline: 28.07.24 Please RT More info: shorturl.at/5ZP7R

What if we could universally recombine, insert, delete, or invert any two pieces of DNA? In back-to-back nature papers, we report the discovery of bridge RNAs and 3 atomic structures of the first natural RNA-guided recombinase - a new mechanism for programmable genome design

Check out the latest story from the Sternberg group: phages coopted transposon-encoded nucleases (TnpB) and repurposed them for regulation of host genes! nature.com/articles/s4158… Thrilled to see this work in print, & a huge thanks to my amazing co-authors!!

Phage predation accelerates the spread of plasmid-encoded antibiotic resistance | Nature Communications nature.com/articles/s4146…

Modified peptides produced by bacteria protect from phage infection - congrats Helena Shomar and Aude Bernheim for this fantastic discovery! Can these new antiviral molecules also inhibit viruses that infect humans? 🤔

Professor Charged for Operating Multimillion-Dollar Grant Fraud Scheme Wang allegedly engaged in a scheme to fabricate and falsify scientific data in grant applications made to the NIH on behalf of himself and the biopharmaceutical company. $SAVA justice.gov/opa/pr/profess…

New from the lab: sedentary integrons as biobanks of defense systems (see Eloi Littner 🧵). 10% of the model integron cassettes have anti-phage activity. As there are > 25,000 different families of integron cassettes in RefSeq we’re far from knowing all bacterial immune systems!

Scientists have designed a gene-editing tool that can modify bacterial populations in the gut microbiome of living mice go.nature.com/3S3y5QJ

Called it. CDC is now recommending that all wastewater surveillance groups develop and implement protocols to specifically test for H5N1. 👏👏👏

Keen to help us end the unsustainable trade in painted woolly bats ? We are raising funds for much needed on-the-ground research. Every little bit helps. globalgiving.org/projects/save-…