Prof Derek Connolly (@drderekconnolly) 's Twitter Profile
Prof Derek Connolly

@drderekconnolly

Consultant Cardiologist
Midland Metropolitan University Hospital & Birmingham City Hospital
Also now on BlueSky

ID: 3007352614

linkhttps://www.drderekconnolly.com/ calendar_today31-01-2015 09:03:04

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TIMI Study Group (@timistudygroup) 's Twitter Profile Photo

Essence – TIMI 73b met its primary endpoint with olezarsen, an ASO targeting APOC3, robustly reducing levels of triglycerides! Look forward to sharing more details at an upcoming scientific congress. Brian Bergmark

Erfan Tasdighi (@erfantasdighi) 's Twitter Profile Photo

Excited to share the first time ever 🥁 "Sex-Specific CAC Percentiles Across South Asian Adults in U.S." 65% of men and 30% of women have CAC >0 by 55 ~75th percentile for 55yo SA men or 65yo SA women is absolute CAC score of 100 link: bit.ly/43l9TOw JACC Journals

Excited to share the first time ever 🥁

"Sex-Specific CAC Percentiles Across South Asian Adults in U.S."

65% of men and 30% of women have CAC >0 by 55

~75th percentile for 55yo SA men or 65yo SA women is absolute CAC score of 100

link: bit.ly/43l9TOw
<a href="/JACCJournals/">JACC Journals</a>
GoggleDocs (@goggledocs) 's Twitter Profile Photo

♻️ 💔Recovered EF ≠ recovered risk Finerenone delivers—LVEF history doesn’t change that 🔹 HFimpEF = 5% of trial pop, median EF rise: +12% 🔸 CV event rates still high (21.4 vs 16.0 per 100 pt-yrs) 🔹 Finerenone benefit consistent: RR 0.72 in HFimpEF 🔸 Greater absolute risk

♻️ 💔Recovered EF ≠ recovered risk
Finerenone delivers—LVEF history doesn’t change that

🔹 HFimpEF = 5% of trial pop, median EF rise: +12%

🔸 CV event rates still high (21.4 vs 16.0 per 100 pt-yrs)

🔹 Finerenone benefit consistent: RR 0.72 in HFimpEF

🔸 Greater absolute risk
Davide Capodanno (@dfcapodanno) 's Twitter Profile Photo

#EuroPCR simultaneous publication. In the 4D-ACS trial, one-month DAPT followed by prasugrel 5 mg monotherapy in ACS patients treated with a drug-coated stent reduced NACE by 49%, primarily driven by a 77% reduction in bleeding events, compared to 12-month DAPT. What I find

#EuroPCR simultaneous publication. In the 4D-ACS trial, one-month DAPT followed by prasugrel 5 mg monotherapy in ACS patients treated with a drug-coated stent reduced NACE by 49%, primarily driven by a 77% reduction in bleeding events, compared to 12-month DAPT. 

What I find
Prof Derek Connolly (@drderekconnolly) 's Twitter Profile Photo

Wonderful symposium on cardiovascular risk in Helsinki 🇫🇮at the European Stroke meeting with great friends and a brilliant audience #ESOC2025

Wonderful symposium on cardiovascular risk in Helsinki 🇫🇮at the European Stroke meeting with great friends and a brilliant audience #ESOC2025
Tom Hyde (@cotscardiology) 's Twitter Profile Photo

Interesting can anyone else see the potential for CTCA in primary prevention of CVD with low dose and RCT evidence, other omics are there in the retina etc but Sutton's law says go for the ❤️. This is what we want the Coronary Clinic of the future Ronald P. Karlsberg MD FACP FAHA FACC MSCCT | Dr Scott W Murray

Prof Derek Connolly (@drderekconnolly) 's Twitter Profile Photo

Lp(a)-associated CAD risk seems to particularly affect those having levels of Total-C, LDL-C and TG above the thresholds from clinical guidelines

Prof Kausik Ray FMedSci (@profkausikray) 's Twitter Profile Photo

Our latest paper . G lo al variations in LP(a). Levels f rpm 6 WHO regions. Implications for trials and access to therapies in JACC Journals doi.org/10.1016/j.jacc…

Our latest paper .  G lo al variations in LP(a). Levels f rpm 6 WHO regions. Implications for trials and access to therapies in <a href="/JACCJournals/">JACC Journals</a> 

doi.org/10.1016/j.jacc…
Prof Kausik Ray FMedSci (@profkausikray) 's Twitter Profile Photo

Here’s the link to our LPa analysis from 13 countries published yesterday. Great editorial by Ron Blankstein kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

SWBH Charity💙 (@swbhcharity) 's Twitter Profile Photo

Welcome to ‘Bright Futures’ our new Your City & Metropolitan Hospitals Charity newsletter, supporting the Sandwell & West Birmingham NHS Trust. Click on the link to view all our latest stories from our fantastic fundraisers. Thank you to all our supporters.rb.gy/c76qb7

Welcome to ‘Bright Futures’ our new Your City &amp; Metropolitan Hospitals Charity newsletter, supporting the Sandwell &amp; West Birmingham NHS Trust. Click on the link to view all our latest stories from our fantastic fundraisers. Thank you to all our supporters.rb.gy/c76qb7
Prof Derek Connolly (@drderekconnolly) 's Twitter Profile Photo

25 years ago, as a young cardiologist in Cambridge, I took a call on a weekend from a hospital with no pacing facilities about an elderly lady with a heart rate of 30 in complete heart block. I brought her over, popped in a pacemaker and send her home Then this happened

25 years ago, as a young cardiologist in Cambridge, I took a call on a weekend from a hospital with no pacing facilities about an elderly lady with a heart rate of 30 in complete heart block. 

I brought her over, popped in a pacemaker and send her home

Then this happened
GoggleDocs (@goggledocs) 's Twitter Profile Photo

💉 Zilebesiran: A shot in the arm (well, tummy) for BP control 600 mg SC x1 in #KARDIA2 → SBP ↓ by: ▪️ −12.1 mmHg (indapamide) ▪️ −9.7 mmHg (amlodipine) ▪️ −4.5 mmHg (olmesartan) 🧬 siRNA blocks hepatic angiotensinogen = durable RAS inhibition ➡️Now in Phase 3 (600

💉 Zilebesiran: A shot in the arm (well, tummy) for BP control

600 mg SC x1 in #KARDIA2 → SBP ↓ by:
▪️ −12.1 mmHg (indapamide)
▪️ −9.7 mmHg (amlodipine)
▪️ −4.5 mmHg (olmesartan)

🧬 siRNA blocks hepatic angiotensinogen = durable RAS inhibition

➡️Now in Phase 3 (600
ESC Council on Stroke Chairperson (@escstrokechair) 's Twitter Profile Photo

📣Whether you're treating #AFib or just trying to stay on top of the latest, join Dr. Jose Joglar & Prof. Gregory Lip as they break down the latest U.S. and European guidelines 👇👇👇 tinyurl.com/2h5t4djz Vasculearn Network Liverpool Centre for Cardiovascular Science Jacopo Imberti Francesco Vitali Luca Bergamaschi

Prof Derek Connolly (@drderekconnolly) 's Twitter Profile Photo

This week I was delighted to be interviewed by my amazing friend Prof. Aleks Subic for a new Aston University podcast called “Game Changers” coming this Autumn As you can see,we even got the old Stratocaster out Aston University is truly the coolest university ever #Astonbury

This week I was delighted to be interviewed by my amazing friend <a href="/ProfAleksSubic/">Prof. Aleks Subic</a> for a new <a href="/AstonUniversity/">Aston University</a> podcast called “Game Changers” coming this Autumn 

As you can see,we even got the old Stratocaster out 

Aston University is truly the coolest university ever #Astonbury
British Cardiovascular Society (@britishcardioso) 's Twitter Profile Photo

Get ready for #BCS2025 📱 Our Annual Conference starts on Monday, so make sure you're prepared by: ☑️ Downloading the official BCS Annual Conference App ☑️ Viewing the programme and favouriting sessions you want to attend ☑️ Securing your spot in the Education Zone ☑️ Booking

John Kastelein (@johnkastelein) 's Twitter Profile Photo

Sam Tsimikas, MD Hi Sam , it appears that obi’s effect on Lpa levels in the 50 to 150 nmol/L range is about double the size of what the PCSK9 inhibitors have reported in that range ..