Dragana Despotovic
@draganades
Scientist at Institute of Molecular Genetics and Genetic Engineering
ID: 1218824303317344257
19-01-2020 09:15:48
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Danny was inspired by phosphate binding loops (PBLs), which are some of the most ancient structures in biology. For the Protein Science issue in his honor, Hayate Hirai and I took a look at a lesser-known PBL that lies at the heart of Nat/Ivy proteins. onlinelibrary.wiley.com/doi/abs/10.100…
With just a handful of added reactions (hint: non-autocatalytic purine synthesis) we chart a path from ancient geochemistry to modern metabolism. A collaboration with network expansionistas and world-class peer mentors Josh Goldford and Harrison Smith. biorxiv.org/content/10.110…
The Ancient Protein Saga Continues -- Our New Manuscript on the functional ambidexterity of an ancient domain is now available. Liam M. Longo The Metanis Group
Electrons act like they are spinning. Amino acids are chiral. These two facts shape protein interactions in ways you probably haven't considered. Check out this CISStacular study lead by the baahubali of biopolymers Pratik Vyas in the Naaman group. biorxiv.org/content/10.110…
Great work from Longo lab (Liam M. Longo )
Need phosphorylating power? Maybe our universal polyphosphate kinase can help! ATP✅ GTP ✅ CTP ✅ UTP ✅ in vitro transcription ✅ An energizing collaboration with matsuura_tomoaki. Check it out here: biorxiv.org/content/10.110…
Redefining the Limits of Functional Continuity in the Early Evolution of P-Loop NTPases Now out in Molecular Biology and Evolution Exciting collaboration with Caroline Lynn Kamerlin 🇺🇸🇬🇧🇸🇪🇮🇷 ☀️ 🇪🇺🦓 academic.oup.com/mbe/advance-ar…
Small, ambidextrous HhH motif is now in Angewandte Chemie
Is phylogenetics the only record of protein history? No! Led by Tatsuya Seamus Corlett, we show that the history of enzymes is written into the structure of metabolism. From there, we reconstruct a self-consistent model of metabolic and enzyme evolution. biorxiv.org/content/10.110…