Registrations are open for the biggest European proteomics conference in 2023. conferences.ncl.ac.uk/bspr-eupa2023/ Great programme, great speakers! Early bird registrations until April 9th. Come and visit Newcastle. #Proteomics #TeamMassSpec British Society for Proteome Research News@EuPA

BSPR and EUPA #proteomics conference 2023 in Newcastle! Early bird registration deadline this weekend! British Society for Proteome Research News@EuPA

Fresh data from the brand-new BrukerMassSpec timsTOF HT: human xenograft model in mouse liver. 500 ng protein digest, 1 hr gradient, diaPASEF with library, searched with DIA-NN: - 13,909 protein groups (of which >8,000 human) - 165 peptides - 953k PSMs

Looking forward to the Bruker post meetup in #Edinburgh, just finalising a few slides and enjoying the view! Matthias Trost 🇪🇺

Huge congratulations to Amy L. George on her paper🤩🙌 Thanks to everyone involved! Check out her poster (No.37) at the #BSPREUPA2023 next week British Society for Proteome Research News@EuPA @Trostlab #TeamMassSpec #proteomics pubs.acs.org/doi/10.1021/ac…

Looking forward to #BSPREUPA2023 where I get to show some data and applications of the Bruker TIMS ToF-HT. If you want to see the real deal you'll have to come to poster 145!

When you're trying to sleep after the @mjmaccoss plenary talk, but can't stop thinking about the monstrous complexity in your datasets that you are probably missing #BSPREUPA2023

I use Alexey Nesvizhskii fragpipe tools Matthias Trost 🇪🇺 for fairly typical proteomics searches, but now I gotta go find all that complexity I'm sure I am missing in my datasets! #BSPREUPA2023

What a great night at the Wylam Brewery with the Matthias Trost 🇪🇺 at #BSPREUPA2023, thanks Bruker

Normalisation (and if we should be doing it and how) keeps me up at night. Thanks for discussing it Alejandro Brenes #BSPREUPA2023

#BSPREUPA2023 . What a week! It's been great fun to be part of the organisation team, present my research and to hear about all of the amazing proteomics research going on. Now to sleep....

This toy example may change how you look at tSNE & UMAP. They find clusters in the most uniform data possible.

Had a good chuckle @ProteomicsNews 's Vadim Demichev meme. Also, added "look into cloud computing for proteomics" to the to do list (can I run DIANN faster???) #quantms researchsquare.com/article/rs-300…

Everyone who is happily reporting crazy ID numbers on Astrals, please read the @mjmaccoss paper carefully. It is very good. The 10% false (or at least non-quantitative) precursor IDs translates to even higher false protein level FDR. Let’s not go back to the proteomics circa 2001

How do #macrophages reprogram following the uptake & digestion of apoptotic cells? Can these macrophages then trigger naïve cells? We employed SILAC and DIA-MS to answer these questions in our latest preprint. Matthias Trost 🇪🇺 Andrew Frey Check it out here: biorxiv.org/content/10.110…

"Pancakes in space" is a quality analogy for DIA PASEF, thanks Juan, Talus Bio #ASMS20204

Should have posted yesterday, but glad to be here at #ASMS2024 Matthias Trost 🇪🇺 NUPPA

I have diligently ironed my poster for the cleanest possible presentation tomorrow #ASMS2024 come chat about DIA PASEF, unusual samples, data analysis decisions, and high throughput proteomics in general. TP184.

When you get back in the lab after experiencing a substantial knowledge spike after #ASMS2024

Thanks to colleagues and collaborators: Katarzyna Mikruta (Jagiellonian University); Carsten Scavenius, Jan Enghild (Aarhus); Andrew Frey Adam Hart, Arnaud Baslé,Matthias Trost 🇪🇺 Robert Hirt, Bert van den Berg (Newcastle).