Sunday. Not tragic—just... off. In my latest piece, I explore the Sunday Blues: From Puritan guilt to postwar conformity to modern restlessness. Why does free time sometimes feel so heavy? docsopinion.com/the-sunday-blu…

Episode 7 of my series, The Heart of Power, explores what happened when the most resilient figure in American politics faced a battle he couldn’t spin, control, or survive without scars. 📰 Read: The Enemy Inside – Nixon’s True Final Battle docsopinion.com/the-heart-of-p…

Sleep tracking was supposed to help us rest. Instead, it created a new disorder: orthosomnia ... My latest piece explores how wellness turned into performance. 🔗 Orthosomnia: A Wellness Disorder by Design docsopinion.com/orthosomnia-a-…

The real story isn’t what they told us about fat. It’s what they didn’t. 🕯️ The Ghost in the Guidelines docsopinion.com/the-ghost-in-t…

1 in 5 people carry this risk. Most don’t know it. Most never get tested. Lipoprotein(a) could change how we understand heart disease. New article just dropped 👇 👉 docsopinion.com/lipoproteina/

LDL-C measures cholesterol content. ApoB counts the particles that cause the damage. If we want to understand — and prevent — heart disease, we need to focus on the right number. 📘 New article: docsopinion.com/apolipoprotein…

Why do Sundays feel so heavy—before Monday even begins? My first essay on Substack is live: The Sunday Blues: A Weekly Ache in the Soul of Modern Life #SundayBlues #Substack #Reflection #MentalHealth #Culture 📖 Read here →docsopinion.substack.com/p/the-sunday-b…

🩺 New on DocsOpinion: Inside the Echo Chamber of Cardiology What happens when metrics replace meaning? When we treat risk scores—not people? A personal critique of modern medicine’s self-made silence. Read → docsopinion.com/echo-chamber-o…

The Devil’s Breath open.substack.com/pub/docsopinio…

A massive heart attack in 1955 nearly killed Lyndon B. Johnson. Eight years later, he took the oath beside Jackie Kennedy. He ruled like a man on borrowed time—because he was. 📖 Read: docsopinion.com/the-heart-of-p…

Option 1 — Direct & punchy Most heart attacks don’t start with chest pain. They start decades earlier — with atherosclerosis, step by step. I’m launching a new Substack series: Inside the Artery — 13 Steps of Atherosclerosis. 👉 docsopinion.substack.com/p/inside-the-a…

Step 1: Endothelial Dysfunction — The Trouble Begins This is the first in a 13-part series exploring the biology of atherosclerosis — open.substack.com/pub/docsopinio…

“Doctor, my cholesterol is fine. How can I still have heart disease?” The answer often lies beyond LDL — in VLDL and remnant cholesterol. Here’s what you need to know: docsopinion.com/vldl-triglycer…

Step 2: Lipoprotein Entry into the Intima open.substack.com/pub/docsopinio…

New on DocsOpinion: Brain fog. Real condition or just life in 2025? Screens, stress, dopamine — and a story that drifts through the mist. #BrainFog #Attention #DocsOpinion docsopinion.com/brain-fog-nati…

Step 3: Retention by Proteoglycans Atherosclerosis doesn’t begin when cholesterol crosses the artery wall. It begins when it gets stuck there. — Step 3 in the series is live. open.substack.com/pub/docsopinio…

A Letter from Reykjavik — What Are We Trying to Save? open.substack.com/pub/docsopinio…

He kept JFK upright. He hid LBJ’s failing heart. He signed the death certificate, stood in both Dallas and Bethesda — and never told what he knew. George Burkley: the White House doctor who knew too much. docsopinion.com/the-heart-of-p… via Axel F Sigurdsson MD

Medicating Appetite: The GLP-1 Dilemma Hunger used to be a signal of life. Now it’s something we medicate. docsopinion.com/medicating-app… via Axel F Sigurdsson MD

Step 5 is out. The fire starts here — the activation of innate immunity. My series on the biology of atherosclerosis continues. docsopinion.substack.com/p/step-5-activ…