🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

What happens to all those alternative transcripts? 👉 Many are translated 👉 Proteolytic processing adds even more diversity Integrated mRNA & protein isoform landscape now out on bioRxiv! doi.org/10.1101/2025.0… #proteomics #transcriptomics #systemsbiology

Want to know how the ligands interact with proteins beyond model human cell lines? Interested in membrane targets? Check out our High-Throughput PELSA method which allows you do all these cool screenings for dozens of ligands within 2 hours! biorxiv.org/content/10.110…

Excited to share our preprint on multiplexed DVP! mxDVP extends CODEX to DVP family, revealing spatial heterogeneity in human pancreatic islets with 12 endocrine sub-types including rare polyhormonal cells. Fantastic team effort Emma Lundberg #LundbergLab biorxiv.org/content/10.110…

Check out ADAPT-MS: our flexible, scalable diagnostic framework that transforms discovery plasma proteomics directly into clinical decisions. Dynamic retraining enables single-sample diagnostics for any task - no imputation or fixed panels needed. doi.org/10.1101/2025.0…

Excited to be hosting next week’s DFCI TPD seminar! We’ll hear from two outstanding speakers, Rebecca Metivier and Martin Steger who will share their work on developing and applying mass spectrometry-based proteomics platforms to identify and catalog degrader targets.

To bead or not to bead? We evaluate five plasma proteomics workflows, finding bead-based methods enhance detection but show high susceptibility to cellular contamination bias. Strategies to optimize biomarker discovery in plasma proteomics. doi.org/10.1101/2025.0…

I am excited to see our performance assessment of the successor of Scanning SWATH on the Zeno TOF7600+ mass spectrometer - ZT Scan DIA - pre-printed (biorxiv.org/content/10.110…).

🚨 New preprint! 🚨 Presenting diaPASEF immunopeptidomics for bacterial epitope discovery. 💥 Showcasing DIA-NN immunopeptidomics using proteome-wide predicted HLA class I libraries! 🧬 Read more: biorxiv.org/cgi/content/sh… #Immunopeptidomics #MassSpec #DIA #HLA

Was great to contribute to this fantastic work led by Patrick Willems. With the new proteoform confidence module in DIA-NN, we enabled non-specific digest searches. Here's how it now works for immunopeptidomics!

New preprint alert! We benchmarked 5 plasma enrichment methods and built an automated, cost-efficient MagNet workflow. Up to 4,200 proteins/sample identified with DIA on timsTOF Pro 2—at just a few dollars/sample. doi.org/10.1101/2025.0… Evosep Bruker

We present SPIED-DIA – a spike-in enhanced phosphoproteomics method combining DIA with targeted sensitivity to uncover synergistic signaling in colorectal cancer cells. 👉 [rdcu.be/enPF2](rdcu.be/enPF2)

Join our #ASMS Breakfast Seminar on Monday, June 2, where Ashok Dongre, Senior Director and Head of #Proteomics at Bristol Myers Squibb, will share his latest research on the next generation of #Evosep chromatography workflows. Register now at evosep.com/asms2025 #teammassspec

Multiplexed proteomics is getting a big boost 🚀 It's not just speed & scale ... It's also data quality, depth, rich spectra improving de novo sequencing & accurate quantification. biorxiv.org/content/10.110…

The Nesvizhskii lab has 9 members attending #ASMS2025! 9 posters, contribution to 4 evening workshops, and one Bioinformatics Hub on #FragPipe. Plus multiple collaborative posters with other groups. See you in Baltimore!

Happy to announce that the development version of DIA-NN has preliminary support for multi-column setups that allow acquiring multiple samples in the same run, in collaboration with Coon Lab. See SynchroSep-MS poster by Noah Lancaster for the concept.

Protein digestion in 200 nL on solid-phase tips: SPEC enables low-input proteomics—even with SDS/SDC at high levels. From FFPE and muscle to high throughput plasma. SPEC is a universal and Evosep-compatible protocol. biorxiv.org/content/10.110…

Mathias Wilhelm, Martin Frejno from MSAID as well as Marie Locard-Paulet, Magnus Palmblad and myself are organising a workshop on FDR control & trustworthiness of proteomics, hosted by Lorentz Center in Leiden, February 2-6, 2026. Stay tuned :) lorentzcenter.nl/trustworthines…

I’m thrilled to share that the main work of my PhD has been published Cancer Cell! With Matthias Mann Lab & Ernst Lengyel, we analyzed the progression from ovarian serous borderline tumors to invasive cancer using spatial proteo-transcriptomics and identified new therapeutic targets.

#Proteomics collaboration was never easier. Our multi-lab study showcase how standardized, automated workflows with #EvosepEno deliver consistent, high-quality results across labs and instruments. Get the full story: evosep.com/wp-content/upl…