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Dr Christine Sempoux Histology of these vascular changes highlighted in this great paper: pubmed.ncbi.nlm.nih.gov/29644430/ #USCAP2025 #Liverpath

Dr Christine Sempoux What is recommended now for histologic terminology? pubmed.ncbi.nlm.nih.gov/30129657/ In: portal vein stenosis Out: obliterative portal venopathy 👀Trichrome and elastics can help you see #USCAP2025 #Liverpath

Dr Christine Sempoux The histology can be subtle! May need to use stains and IHC to help highlight the normal structures. #USCAP2025 #Liverpath

Dr Christine Sempoux All 5 features should be described in biopsies: portal vein sclerosis, portal/periportal vascular changes, NRH, architectural abnormalities, sinusoidal dilation Recent Gnomes editorial: pubmed.ncbi.nlm.nih.gov/39665793/ #USCAP2025 #Liverpath

Dr Christine Sempoux 🧐More studies needed! ❔️We don't know the frequency ⚠️Overdiagnosis possible (remember that portal veins are not expected in all portal tracts) #USCAP2025 #Liverpath

Dr Christine Sempoux How do biopsies usually come to us? #USCAP2025 #Liverpath

Dr Christine Sempoux 🗨PSVD is a term describing a pattern with multiple causes; is not synonymous with non-cirrhotic phtn! 🔬Histologic lesions described; standard terminology suggested ❔️We don't know ow significance of changes in absence of phtn #USCAP2025 #Liverpath

Andrew Bellizzi 🇺🇦 🩸CD34 can help you determine if you're in a lesion (usually increased) 🕸Retic, GS, and Glypican helpful for malignant vs not (mitoses, too) 🗺Map-like GS can be hard to interpret on biopsy! #USCAP2025 #liverpath

Thank you, John Hart, MD, for your hard work as Chair of our Membership Committee from 2022-2025! 💛💚

Thank you so much, Hans Popper Hepatopathology Society for this honor!

DILI harms patients and remains a TOP reason drugs are withdrawn from the market. Recommend this article by Naga Chalasani et al in HEPATOLOGY Journal reviewing preclinical and clinical testing, DILI adjudication during trials, and how regulators approach NDAs. journals.lww.com/hep/Fulltext/9…

Did you know that selective androgen receptor modulators, anabolic steroids and some body building supplements can cause #DILI ? Patients display cholestasis +/- pruritus. Tomorrow 11am EDT/8am PDT AASLD HepTox SIG is hosting Drs. Andrew Stolz and David Kleiner who will

New DILIN publication alert by esteemed Investigator Dr. Paul Watkins using blood-based transcriptomic biomarkers to aid in the diagnosis and prognosis of idiosyncratic #DILI pmc.ncbi.nlm.nih.gov/articles/PMC11…

A mentor, colleague and friend, Theo is an excellent physician-scientist working to establish knowledge and develop new cures for chronic liver diseases. This is what we do at NIH NIDDK

Theo Heller is one of the most insightful and caring physician-scientists I've ever worked with. A true gem. NIDDK

Excited to present our research at EASL, looking forward to an amazing meeting

At EASL, sharing pathology insights with our hepatology community. Tons of learning all around. EASLnews

What defines success in a Clinical Research Network? From the great Jay Hoofnagle at the #DILIN meeting - Elucidate pathogenesis of disease - Place findings in public domain - Stimulate research - Decrease morbidity and mortality of dz - Publications are not the end game

AI is awesome!! Made with Veo3! Vimentin infomercial #pathology #IHC Sanjay Mukhopadhyay Andrew Bellizzi 🇺🇦

We are excited to announce that Oyedele Adeyi, M.D., FRCPC, is joining UAB Pathology as the Division Director of Anatomic Pathology! Read more about Dr. Adeyi here: bit.ly/3FA1f70