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Here is my writeup of the powerful methods that Irv Weissman, Daniel Dan Liu and colleagues created to isolate and track the development of human neural stem and progenitor cells. Bravo! med.stanford.edu/stemcell/news/…

Was wonderful to be back in Montana's Bitterroot Valley for the Weissman lab retreat after a 3 year hiatus. Thank you as always to Irv and Ann for opening their home to us, and to Rocky Mountain Labs for hosting our talks!

Grateful to Wu Tsai Neurosciences Institute and the Kuo Family to be recognized for our work on human brain development at the 10th Annual Wu Tsai Neurosciences Symposium!

A thought-provoking study from the lab: hematopoietic stem cells (HSCs) get myeloid-biased with age, at the expense of lymphoid cells. Could we rejuvenate the immune system by depleting biased HSCs, restoring B and T cell generation to fight infections? nature.com/articles/s4158…

Fantastic work from the Loh lab generating human blood stem cells (HSCs) with more faithful transcriptomic identity—foundational for many potential cell therapy applications. The million dollar question now: what are the final hurdles to robust multilineage engraftment in vivo?

The lung is home to two types of macrophages—alveolar & interstitial—but it turns out they have drastically different responses to viral infection. Interesting implications for COVID-19 initiation and pneumonia, and a fun collaboration with my good friend and roommate Timothy Wu!

That’s a wrap! Thank you to all of the 2024 Neurobiology GRS attendees for the amazing talks, poster presentations, and engaging discussions. Congratulations to our new co-chairs Ellen Gingrich and Daniel Matúš! 2026 Neurobiology GRS is in great hands!

A week of amazing science and people at the 2024 Neurobiology Gordon Research Conferences in beautiful Tuscany—grateful for the opportunity to share our work dissecting stem cell hierarchies in human brain development!

Our 2024 CSHL conference on human brain development and stem cell models is in full swing, with over 300 participants! This year’s event features exciting new discoveries and dynamic discussions, driven largely by the energy & insights of trainees. A privilege to organize this

Excited to share this work from the Garcia Lab out today in Nature Communications! We engineer "cytokine adaptors", molecular switches that simultaneously block a target cytokine while inducing local activation of alternative cytokine receptors. rdcu.be/ec7GS

Weissman Lab representing at the ISSCR Athens International Symposium on Neural Stem Cells! Glad to share our work on purifying neural stem/progenitor cells from the human brain, and a preview of our work using those cells to model glioma heterogeneity.

Looking forward to meeting this amazing group of neuroscientists at the U of Utah Department of Neurobiology Rising Stars Symposium!

Such a pleasure to have been part of this symposium!

Cortical Development 2022 was the first conference I ever attended, and so it was particularly special to return to Sicily for Cortical Development 2025 Sicily as a speaker. Featuring a sneak peak on some exciting new findings on neural stem cells in the postnatal human brain (stay tuned!)