Our paper regarding ”spontaneous" molticolor bioluminescence imaging was published at PNAS. This technology can be applied to wide range of living supecimen including bacteria, animal and plant. Addition of a luminescent substrate is no longer required.　pnas.org/doi/10.1073/pn…

Bacteria displaying cytokines heat up the tumor microenvironment #NBTNV go.nature.com/3XRyVSv

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

🚨Job alert! 🔬 I have 2 open positions (1 postdoc, 1 senior technician) in my lab (santosmorenolab.org) in Barcelona UPF Medicine and Life Sciences @the_PRBB funded by European Research Council (ERC) If you are passionate about #SynBio and #GeneCircuits, apply now! 🔧🦠 Info below👇 Please RT!

🚨 Postdoc or PhD opportunity! 🕸️ Protein-protein interaction networks face challenges like high error rates and biased degree of certain proteins. Help us improve their quality and develop computational methods to better interpret them! More info: schaeferlab.org/misc/join/"

Finally out after peer review. The first SuperIntegron-less Vibrio cholerae... and it is virtually identical to the WT! doi.org/10.1093/nar/gk…

i think about this a lot

Very proud of this milestone: Company founded (i-Seq Biotechnology) based on findings and technology from our lab Université de Lausanne: VIC Tech Announces Formation of i-Seq Biotechnology to Pioneer Broad-Spectrum Vaccines and Therapeutics prn.to/3Y8Nm51

Humbled and honoured to receive the “Margarita Salas” National Research Award from Ministerio de Ciencia, Innovación y Universidades. The award belongs to my stellar mentors, collaborators, coworkers, and lab members. They are the giants' shoulders on which I stand every day. Now, let's open the champagne!! 🍾🕺

I knew something big was waiting for you, but this is not big, this is huge!! So proud of you and so well deserved! Looking forward to celebrate with that champagne

Very proud of the iGEM UPF 2024 - SkinBAIT team from UPF Medicine and Life Sciences UPF Barcelona who won a Gold medal 🏅at the 2024 #iGEM competition! 👏👏👏 iGEM Community Find out more about the project and the fundraising campaign: - Project: 2024.igem.wiki/upf-barcelona/… - Fundraising: giving.upf.edu/ca/skinbait

TIL that E. coli K12 — the most widely used strain of bacterium for biological research — is named "K-12" because it was first isolated from a diphtheria patient staying in room K-12 of a Stanford University hospital in 1922. Naming conventions in biology are weird!

Highly multiplexed design of an allosteric transcription factor to sense new ligands doi.org/10.1038/s41467…

SynBio Turing patterns in E.coli. I've seen this amazing project progress over the last few years at Imperial and excited that it's now published. Well done to all involved! cell.com/cell-systems/f…

Could one envision a synthetic receptor technology that is fully programmable, able to detect diverse extracellular antigens – both soluble and cell-attached – and convert that recognition into a wide range of intracellular responses, from transgene expression and real-time

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. Djenet Bousbaine led the charge... nature 1/55

In new work led by Aditi Merchant with Samuel King, we prompt engineer Evo to perform function-guided protein design with high experimental success rates, including designs that go beyond natural sequences. We also release SynGenome, the first AI-generated genomics database. 🧵 1/N

Our latest work on Biocomputation in Bacterial Consortia is out in Nucleic Acids Res 😀. In a process we term "intercellular CRISPRi", filamentous phages transmit DNA messages from sender to receiver cells to regulate gene expression by CRISPR interference. doi.org/10.1093/nar/gk…

📢Excited to introduce NanoCas -our new mini CRISPR system that can reach tissues previously out of reach! By shrinking CRISPR to 1/3 its normal size, we can now edit genes in muscle, heart & brain that were difficult to access before. Summary & link to paper:

So excited to share our new paper out today in nature. We repurposed R2 retrotransposons to create STITCHR, a tool that can make diverse edits in mammalian genomes including scarless multi-kilobase scale insertions nature.com/articles/s4158…