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Thrilled to see our #microbiome #immunology paper is out in nature! We mapped T cell receptor specificity to the gut microbiome at the level of a single TCR versus a single strain. nature.com/articles/s4158… Here are highlights of our findings.

Infant gut phageome. Yue Clare Lou, Ph.D. The Banfield Lab characterize preterm & full-term infant gut phageome succession during first 3 yrs. 9% of #phage strains establish long-term residency. Stop codon reassignment&tail fiber mutations may aid viral gut colonization cell.com/cell-host-micr…

Exciting new work from our lab describing a novel platform for MHC-II recognition, called TRACeR, that uses just a single loop! Congratulation to Haotian Du, Jingjia Liu, and the team biorxiv.org/content/10.110…

A large-scale, whole-genome analysis in Science of over 12,000 cancers reveals previously unreported mutational signatures, including tumor-specific rare signatures. The findings may enhance personalized cancer treatments and diagnoses. #WorldCancerDay scim.ag/5KY

If you are interested in entrepreneurship, check out the WIES fellowship program!

So happy to see our work published at Cell ! We added the quaternary structure dimension to proteome-wide, #AlphaFold2 predictions: The published paper: sciencedirect.com/science/articl… The original 🧵 (Two more experimental structures since!) x.com/ElevyLab/statu…

The SaaS startup playbook doesn’t work in deep tech. “Move fast and break things” doesn’t apply when building nuclear reactors or bioengineering cell therapies. That’s why we built 5050, “a cheat code for starting a deep tech startup.” (quote from an alumni) Applications open!

If true, is this a Nobel prize? cell.com/cell/abstract/…

Our immune system is amazing, but faces pandemics, cancer and aging. It's also wired to reject what we need to extend our healthspans & minds: organs, implants, new genes. It's time to radically augment it. We need to build an immune-computer interface (ICI). A manifesto🧵!

Check out this study from #AACR24 opening plenary speaker Jakob Nikolas Kather: a decentralized, privacy-preserving ML framework used to train an #AI system identifies actionable molecular changes in patients with #ColorectalCancer with routine #histopathology data nature.com/articles/s4159…

How to pick a problem. Today in Cell. 1/53 cell.com/cell/fulltext/…

Discovery of tumor-reactive T cell receptors by massively parallel library synthesis and screening go.nature.com/3Uv5OnG

Congrats Kaz!!

AI in microbiome research: Where have we been, where are we going? Georg K Gerber discusses the evolution of Artificial intelligence and provides a perspective on how AI may impact microbiome research in the next decade cell.com/cell-host-micr…

We’re excited to introduce @ChaiDiscovery and release Chai-1, a foundation model for molecular structure prediction that performs at the state-of-the-art across a variety of drug discovery tasks We're releasing inference code, weights & a web interface: chaidiscovery.com/blog/introduct…

The distribution of ~ 2 trillion immune cells in the human body.

.Megan Molteni's pitch-perfect lineup of the best talent in clinic-enabling gene editing - study their papers as a masterclass and rejoice. Komor Lab @MarsonLab Patrick Hsu Britt Adamson Ben Kleinstiver Kiran Musunuru Charles Gersbach Krishanu Saha statnews.com/2024/10/31/who…

I’m excited to share our latest study led by Giulia Pasquesi out today in Cell Press , uncovering a new way transposons have been repurposed for human interferon signaling! Read on for a thread on cryptic splice variants, decoy receptors, and viruses (1/N) 👇🧵

We generated the world's largest single cell atlas, Tahoe-100M Vevo Therapeutics (larger than all public data combined). We are announcing today that we are fully open-sourcing it. And we are collaborating with NVIDIA Healthcare to train modes of cell state on its data.

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis