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Through this, your Dad also inspires others. You will be an inspiration for many from your town (and beyond).

To teach our kids real life skills - on Sundays they are allowed to run their home cafe for the family. Mom and I mentor and are loyal (only) customers. The two make their own menus and get to keep the money they make. They collaborate and compete. Here is the menu.

New investigators bringing their ideas and energy is always a good thing, for any field. You are welcome. Glad you are focusing on Mtb also.

You may wonder what else kills 1.5 million a year. It's tuberculosis. TB is completely curable & preventable, but because it only kills people in the developing world, those of us with privilege ignore it. Of course we want a Covid vaccine - but let's fix TB too!

Dear graduate students, let this sink in. If you want to read more about what Albert did, I recommend the novel 'the greatest story never told' by Frank Ryan. Just like Albert's, your contributions are much needed and will be valuable to humanity.

Our team has taken one step towards addressing the challenge of developing new #antibiotics. Early results show promise but much work lies ahead to develop one that is useful bedside. We're determined to fight against #AMR, #TB and #mycobacteria. Our paper nature.com/articles/s4200…

An interesting protein with domains reminiscent of a classical PBP, but it also exhibits a strong b-lactamase activity. M. abscessus mutant lacking this protein grows as a single clump and is wiped out from the lungs of mice...Thx PeptidoglycanPapers for sharing this.

Indeed an interesting microbe. Amazing heterogeneity in geno- and phenotypes. A bit more finicky compared to other mycos. Learned much and continuing to learn from this myco..

This series has been a go-to reference for many protocols we use. Thank you for putting these together.

Indeed please join the effort. Antibiotic development/discovery is one of the main challenges of our times as several bugs have become resistant to many Abx we have. A good blog to read more about the need for new Abx is …ibiotics-theperfectstorm.blogspot.com.

Thank you for sharing this. A+ grade evidence of sensing and phagocytosis by a neutrophil. And also of cell polarity and kinetics of cytoskeletal rearrangement to achieve motility. Anyways, how is the neutrophil anchored to the glass tube?

Below a cool teaser of what the microscopy setup from our latest preprint can do. Here, a Salmonella bacterium (arrow) divides on the surface of human intestinal cells. It then invades, and the epithelial cell reacts by instantly killing itself.

Very exciting concepts at the interface of chemistry and infection biology that focus on unexplored yet fundamental aspects of bacterial cell wall.

A good example of a new frontier. Exciting.

Heaven is a myth, Nepal is real! Sunset on a warm day at the lake Phewa 🇳🇵❤️💙💚🧡

Drs. Story-Roller and Pankaj Kumar from our group have led multiple studies providing both molecular mechanistic basis and evidence for efficacy of dual b-lactams vs Mycobacterium abscessus. Here are our publications: sites.google.com/view/lamichhan…