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It took o3 practically a master's thesis worth of work, but *did* correctly read my wrist watch this afternoon!

Our new paper - the first peer-reviewed brain and phenomenological examination of 5-MeO-DMT is out in Neuroscience of Consciousness . TLDR: We tested whether ‘the mount Everest’ of psychedelics could induce a complete state of consciousness deconstruction while preserving awareness. 1/n

This is such a cool paper! One question I have though is around reinforcement and reification. It would seem that the former (driven by dopamine, etc), even when in service of emptiness, is actually the main driver of reification in our own minds. How do we resolve this?

All science should be open. Paywalls are unacceptable.

Carl Jung on avoidance... damn

David Graeber's Bullshit Jobs and Mark Fisher's Postcapitalist Desire are both powerful and sobering reads for anyone who believes that all that stands in the way of AGI ushering in some post-scarcity utopia are merely technical (i.e. "alignment") problems. Unfortunately, both

Excited to share that I will be presenting a talk at the Psychedelic Science 2025 conference in Denver CO on Wednesday June 18th! Would love to meet up with anyone else who is going and is interested in the intersection of computational modeling, psychedelics, and mental health.

I appreciate the openness here, but I disagree with the indecisiveness on key issues. I think the reasoning and system prompts should make the models explicitly discourage emotional connections and deny consciousness. Longer term, we should work towards strong societal norms that

This story is absolutely wonderful, you won't be disappointed!

Arthur Arthur Juliani presenting about applying machine learning conceptual frameworks (overfitting, distribution shifts, synaptic weights landscape, etc.) to the neuroplasticity enhancing effects of psychedelics.

Great news and yet another significant step forward for psychedelic medicine! Today, atai Life Sciences and Beckley Psytech announced (very!) positive topline results from the long-awaited Phase 2b trial of a single dose of BPL‑003 (5-MeO-DMT) in 193 patients living with

Announcing our new preprint on the neuroscience of cessation events as informed by brain criticality The manuscript is titled: “Brain Criticality and Advanced Meditation ‘Cessation’ Events: An Intensively Sampled Electroencephalography Case Study” In this intensively sampled