Therapeutic Targeting of Hypoxia-A2-Adenosinergic Pathway in #COVID19 Patients (Halpin-Veszeleiova and Hatfield) - new in ow.ly/PR7Y50Hn3Am #adenosine #ARDS #hypoxia #inflammation

Great to have this research in preprint! And hopefully soon to be published! 🫀 Chris O'Shea Sophie B-Stringer Jasmeet Singh Toni Malinova Katja Gehmlich Davor Pavlovic Andrew P Holmes biorxiv.org/content/10.110…

Our new article in Journal of Molecular and Cellular Cardiology jmcc-online.com/article/S0022-… demonstrating how differences in the properties of atrial and ventricular Nav1.5 modify the sensitivity to flecainide. Great team effort! Davor Pavlovic Dan Johnson Molly O'Reilly Jasmeet Singh Chris O'Shea Nathan Tucker

Proud of Max Cumberland & the team: 1st paper of PhD (The National Centre for the 3Rs, British Heart Foundation) accepted. Check out this review: frontiersin.org/articles/10.33… Great team effort, involving Blanca Rodriguez, Leto Luana Riebel, Ashwin Roy, Chris O'Shea, Andrew P Holmes, Chris Denning, Paulus Kirchhof RDM Oxford

Chronic intermittent hypoxia, Increases carotid body activity. Propranolol blockade, Can prevent this cascade, Suggesting it’s a beta-adrenergic proclivity.

Nice to see this published today in Scientific Data. Summary: Here's loads of optical mapping data, go nuts. nature.com/articles/s4159… Thanks to great work by great people, Davor Pavlovic Andrew P Holmes Molly O'Reilly and funders Wellcome British Heart Foundation.

My abstract has been selected for oral presentation! 😁 So excited to present our research at European Society of Cardiology #EWGCCE 🫀 Andrew P Holmes Davor Pavlovic Katja Gehmlich Carol Ann Remme Chris O'Shea Amsterdam UMC

Our new review on hypoxic mitochondrial signalling pathways in carotid body oxygen sensing has now been published! frontiersin.org/articles/10.33…. Andy Aga Świderska Hayyaf Saad Aldossary UoB Biomedical Sciences Frontiers - Physiology

Developmental differences in myocardial transmembrane Na+ transport: implications for excitability and Na+ handling 👉 buff.ly/3Qeyi0U

This work could have potentially huge implications! Read the full paper now 👉 buff.ly/3bz7uIG

Our new article in @commsbio reveals a novel and essential role for LKB1 in mediating carotid body function and the hypoxic ventilatory response. This advances our understanding of how we respond to a reduction in blood oxygen. Check it out now: nature.com/articles/s4200…

How can a single point mutation in sodium channel Nav1.5 lead to atrial fibrillation? Find out here ⬇️ Europace #atrialfibrillation #electrophysiology academic.oup.com/europace/advan…

Learn how #obesity causes #AFib through both direct and indirect mechanisms in this new #Review article. #AHAJournals Sharina Olivia Baines Abbie Hayes Katie Tompkins Manish Kalla Andrew P Holmes Chris O'Shea Davor Pavlovic ahajrnls.org/3H32XuB

Interested in doing a PhD measuring cardiovascular and respiratory reflexes? We are currently recruiting self-funded international students to work in our laboratory in the UK. See the this link for more info: findaphd.com/phds/project/c… Andy; Dr Joe Welch; UoB Biomedical Sciences

In our new study we show that anabolic steroids could have dangerous effects on the electrical function of the heart, particularly in those young men who (often unknowingly) have inherited genetic mutations. physoc.onlinelibrary.wiley.com/doi/10.1113/JP… Laura Sommerfeld and Larissa Fabritz Journal of Physiology

A new study, led by Professor Larissa Fabritz and Andrew P Holmes, has discovered a link between anabolic steroid use and heart disease. Find out more here: birmingham.ac.uk/news/2024/anab…

Misuse of anabolic steroids could increase the risk of heart disease. In our latest blog, Andrew P Holmes, Laura Sommerfeld & Professor Larissa Fabritz of University Center of Cardiovascular Science (UCCS) & , discuss their paper recently published in Journal of Physiology. Read more ➡️ buff.ly/3WqxFa1 #HeartHealth

I'm delighted to share that I successfully passed my PhD viva UoB Biomedical Sciences I extend my sincere appreciation to all who supported me throughout this academic journey. Special thanks to my supervisors, Dr Andrew Holmes and Dr Andrew Coney, for their invaluable mentorship.

And that’s a wrap for ISAN 2024 👋 thanks to the organising committees in Oxford and Birmingham, to all the speakers and to everyone who attended. Safe travels!

Laura Sommerfeld (Cardiovascular Sciences (CVS)- UoB University Center of Cardiovascular Science (UCCS)) et al. found that androgenic anabolic steroids combined with plakoglobin deficiency cause pathological atrial electrical remodelling in young male hearts 🫀🧬 📜 Read the #ResearchArticle here: buff.ly/3N0lieL