The field of anti-aging has captured the attention of the public. In this Boston Business Journal story, Alex Plesa discusses how he's looking to make old cells young again with Ichor. #Aging #AntiAging #SyntheticBiology bizjournals.com/boston/news/20…

Thanks to all who joined us for our third Boston Longevity Biotech mixer—especially our amazing speakers Bahareh Behrouz (Vincere Bio), Mahdi Moqri, PhD (Biomarkers of Aging Consortium), and Alex Plesa (george church lab). Deep gratitude to our old friends & co-sponsors Felicis. Can't wait for next time!

Excited to announce the launch of Olden Labs! A company building the world's first automated animal lab. Our goal is to radically accelerate animal research for mankind. longevity.technology/news/olden-lab…

🧬🔬 How can we address the bystander challenge in base editing? Happy to share my first paper from the george church lab! Discover how we're making on-demand genome editing a reality with ultra-precise base editing enzymes coupled with our agRNAs. 🚀🧵👇 biorxiv.org/content/10.110…

1/ 🚨 Excited to share my Postdoc research with @geochurchlab at @harvadmed! Dive into our discoveries on the central dogma of biology, antibiotic resistance, #compbio designs, and #synbio. 🧬🔬 Check our paper: biorxiv.org/content/10.110…

Two big papers came out recently filling out some big knowledge gaps in genome instability. The first beautifully ties together R-loops with Cockayne syndrome, TC-NER, and transcript length. Why is that a big deal? nature.com/articles/s4146…

We need to think about cancer prevention as a strategy for longevity. Over the past century, there have been hundreds of aging theories. Almost all of them, from information theory to telomeres to programmed aging, share damage to the genome as a central driver.

My review on scRNAseq of diabetic wounds and our evolving understanding of fibroblast heterogeneity was published in this month's issue of Biomedicines MDPI! Grateful for wonderful mentors Longaker Lab mdpi.com/2227-9059/12/1…

X community - need your help finding the best med. oncologists + founders working in adv. renal cell carcinoma. My dad’s cancer returned as stage 4 met. to lung + lymph nodes. Please help me make a miracle happen + connect me to the best folks you know in the space! 💙🙏

Now is the time for a bold and audacious UK! The UK invents the future. It's time for scientists to lead and build it here too. 100x more UK scientists are capable of starting civilisation-defining companies. 5050 UK helps them start. Applications are open! The path from

1/ 🧵Announcing CORHORT 6 of the Longevity Biotech Fellowship —the most hardcore community of longevity accelerationists! Join 700 members working to SOLVE aging entirely. ⌛️Deadline: Mar 14 Kickoff Retreat: Mar 31 - Apr 4 in Berkeley. 👉Apply: longbiofellowship.org/apply

One of the most important studies for the longevity field was just released last week, and it does not mention aging once. It's about how genome instability is the cause of Huntington's disease. 🧵

I’m delighted to share our work on scrambling the human genome using prime editing, repetitive elements, and recombinases Science Magazine! Raphael Ferreira @LeopoldParts Tom Ellis, george church @SangerInstitute science.org/doi/10.1126/sc… Lots of changes from the preprint. A🧵

Our genome-scrambling paper is out in Science Magazine 🍳🧬! Huge thanks to everyone at @LeopoldParts and george church labs, especially my amazing collaborator Jonas Koeppel!!!! Many additions to the preprint, so be sure to check out his thread 🧵!! science.org/doi/10.1126/sc…

NIH grants frozen. Discoveries delayed. PhDs pushed out. Academia getting gutted. Innovation must continue. There’s never been a better time for scientists to build startups.

Our work on nucleic acid sensing in live human cells is out 🧬⚫️🟢! Big thanks to Ahmed mahas Lisa Riedmayr george church ! Make sure to check out Ahmed's thread 👇

Just posted a piece I've wanted to write for a long time. Maximum Lifespan vs. Healthspan (or - why you cannot diet your way to live to 140), a 🧵 Take a look at these two mice, from the famous Baker et al. 2016 Nature paper:

Excited to introduce evoCAST: a platform for efficient, programmable gene integration in human cells. This work, product of a close collaboration between liugroup and @sternberglab, has been such a fun journey to help lead throughout my PhD. Huge thanks to all contributors!

Absolutely crazy month for progress in the world of genome instability & DNA repair, especially as pertaining to aging. A few of the most exciting papers, a 🧵:

🧵1/ LBF7 Spain is happening and we're doing something kinda wild: -We’re gathering the smartest people who want to SOLVE AGING -going to a longevity resort in the Spanish mountains -to learn, discuss and ACTUALLY BUILD stuff for 7 days straight Here’s what we’re cooking 👇