Can you safely use propofol in patients with egg or soy allergies? See the answer below in my latest #PharmacyEducationBoard

💯💯💯 Maintenance fluids are the “set it and forget it” of inpatient care. As in, they get ordered and stay ordered for far too long.

The SOFA-2 score updates the 1996 Sequential Organ Failure Assessment, reflecting current definitions, variables, and thresholds to grade organ dysfunction in critically ill adults receiving intensive care. #LIVES2025 ESICM ja.ma/4o73EXI

💬 Editorial: The BICARICU-2 trial finds IV sodium bicarbonate may delay or reduce kidney replacement therapy in #criticallyill patients with severe #acidemia and #AKI, but its effect on mortality remains uncertain. #LIVES2025 ESICM ja.ma/3Lf2b32

When I first started in medicine idea of not using arterial line in ICU patient was seen as crazy I remember asking why we couldn't just use cuff for a few hours on particularly busy 30 hour call shift Now we know that cuff BP would've been fine because of an amazing & bold RCT

➡️ The Sepsis Chain of Survival: A Comprehensive Framework for Improving Sepsis Outcomes 🔗 Each link in the chain is critical and interdependent, though not necessarily applied in a linear sequence. ✅ Read the research in CCM: ow.ly/RhzS50XjsiU #SCCM #CritCareMed SCCM

#Nimodipine-induced BP reductions below personalized limits of autoregulation may be associated with worse functional outcome after aSAH. 🧠 shorturl.at/q8ttl #SCCMNeuro #NeuroICU #NeuroTwitter #NeuroX

SOFA 2.0- New Scoring sytem doi:10.1001/jama.2025.20516

Good evidence that when you don’t have access to fomepizole, oral ethanol and hemodialysis still works well for methanol poisoning!

"Risk factors for thrombo-ischemic complications after andexanet alfa reversal of factor Xa inhibitors" was highlighted as Star⭐ Research at SCCM Congress. Click here to read the abstract from this important work by Dr. Paige Bradshaw & team: loom.ly/gmLGrmg #PharmICU

OCEAN just published in NEJM. In AF patients >1 yr after successful ablation, rivaroxaban did not reduce stroke/systemic embolism/new covert infarcts vs aspirin (0.31 vs 0.66 events/100 pt-yrs; P=0.28). Bleeding higher with rivaroxaban (1.6% vs 0.6%). nejm.org/doi/full/10.10…

☕️ Surprising result from the Does Eliminating Coffee Avoid Fibrillation? (DECAF) RCT! In people who underwent cardioversion for Afib, daily caffeine consumption was associated with *REDUCED* risk of recurrent Afib: 64% vs 47% HR 0.61 [CI 0.42-0.89]; P = .01 🧵 1/

⚠️ TPN does NOT increase risk of INFECTION! 🔎 It is just as safe to put PN through a central line as saline 4 large trials show! 📣 New trial in JAMA Surgery shows early PN REDUCES INFECTION in surgery! 🔗 jamanetwork.com/journals/jamas… 📧 Please comment if you want full papers!

Paul Wischmeyer MD JAMA Surgery Ashley DePriest, RDN, CNSC, FCCM Tom Varghese Jr. MD, MS, MBA, FACS, MAMSE 🇺🇸 Nick Mark MD Ann-Marie Brown PhD-ACPNP 🟧 Keith Siau Nutrition Science Lakshman Swamy ([email protected]) Dr. Suzana Mantovani Tanya Halliday, PhD, RD Kelly Issokson MS RD LDN (she/her)

"Evaluation of prophylactic enoxaparin anti-Xa levels in individuals greater than 150kg" was highlighted as Star ⭐ Research at SCCM Congress. Click here to read the abstract from this important work by Dr. Logan Olson and team 👨‍💻: loom.ly/B03R2eY #PharmICU

117 peak anti-Xa levels were assessed in individuals ≥150 kg. The optimal weight-based enoxaparin dose to achieve a prophylactic anti-Xa peak (0.2-0.4) was 0.34mg/kg twice daily 📉. #PharmICU

🌍 Save the Date! Join us on Nov 17, 2025 (12–1 PM EST) for the Advancing Critical Care Pharmacy: Global Perspectives Showcase, celebrating innovation & impact from pharmacists worldwide! 💊✨

Finally online

Great presentations presented today! ACCP CRIT PRN We are Super proud of our excellent speakers & amazing moderator🌷 Hanine AlMubayedh, PharmD, BCPS, BCCCP Ahmed O. Alenazi

#CPPPLU Highlights Secondary analysis of REVISE trial from ATS Blue Journal found ⬆️ APACHE II score, circulatory failure, thrombocytopenia, & antiplatelet agents ⬆️ the risk of upper GI bleeding 🩸. Pantoprazole & enteral nutrition are protective. #PharmICU Jeff Barletta Salmaan kanji