🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

🚀 Excited to announce #PhyKIT 2.0 has been released! 📊PhyKIT is a multi-tool for #evolutionary informatics with 46 functions! ⏩In 2.0, nearly all functions were rewritten to be faster and more memory-efficient 📨Help shape PhyKIT - new feature requests are welcome

Protein sequencing using ONT nanopore flowcells. Experiments were done on the MinION platform using R9.4.1 flow cells. Run conditions were set with a custom MinKNOW script from Oxford Oxford Nanopore at a temperature of 30 °C, voltage of −140 mV / 3 kHz. nature.com/articles/s4158…

Young clonal raider ant larvae (the little white things) are feeding on secretions from pupae (the larger golden things). These secretions are derived from the molting fluid, and create interdependencies across different ant developmental stages. Orli Snir nature.com/articles/s4158…

Does 6mA exist in eukaryotic DNA? This is our take on this dispute: yes it does, and can be very abundant, but mostly correlates with presence of the MT-A70 writer AMT1. Then, 6mA is associated with transcriptionally-permissive chromatin (H3K4me3) 1/6: biorxiv.org/content/10.110…

The epitranscriptome formed by the growing number of modifications occurring within mRNA transcripts.

What gets erased when you integrate single cell data, and can you recover it? Finally, we know what happens and how to recover the lost signals. So excited to share CellANOVA, published online today in NBT! go.nature.com/4hZnzW5

Reduced regulatory complexity associated with the evolutionary transition to sociality from cockroaches to termites despite ... biorxiv.org/cgi/content/sh… #biorxiv_evobio

My first Preprint from my postdoc @bornberglab Looking at Transcription factors in cockroaches and termites and the regulatory changes that are associated with Eusociality biorxiv.org/content/10.110…

Stronger promoters not only transcribe more RNA but also show higher effective translation rates.

easySCF: A Tool for Enhancing Interoperability Between R and Python for Efficient Single-Cell Data Analysis academic.oup.com/bioinformatics… 🧬🖥️🧪 github.com/xleizi/easySCF

We’re offering 3 fully funded PhD positions to explore: 1) Neuron diversity in ctenophores 2) Vision in mosquitos 3) paediatric brain tumour 💡 Projects combine experimental & computational approaches. ⏳ Deadline: Early January. 🌟 Apply now: findaphd.com/phds/?Keywords… Please RT!

Recent studies have revealed unexpected Y chromosome diversity and suggest that the Y may play an outsized role in evolution. @_Axeman_and I wrote this perspective for @EvolLetterswith a few suggestions and requests. academic.oup.com/evlett/advance… Images by jacelyn

If you have ever wondered whether the PAML documentation could be more interactive... We have good news for you! The PAML GitHub repository has been updated and a fresh PAML Wiki is now available for you to navigate the PAML documentation! 📄💻 (1/n) github.com/abacus-gene/pa…

Online Now: Long-range regulation of transcription scales with genomic distance in a gene-specific manner dlvr.it/TGXV8Y

Thank you European Research Council (ERC), feeling truly challenged by this project and can't wait to see it unfold 🪁 The list of people to thank for the support is way too long, but I'm super grateful for everyone there ❤️

AIDO.Cell: Scaling Dense Representations for Single Cell with Transcriptome-Scale Context biorxiv.org/content/10.110…

Two stages of evolution... Grant Kinsler Gavin Sherlock Dmitri Petrov use #ExperimentalEvolution in yeast to show that while 1st-step mutants appear pleiotropic in nature, 2nd-step mutations show a shift towards modular adaptation #PLOSBiology plos.io/4glXoXJ

After 4y in the making, I am super excited that my main PhD project is published 🎉🥳🎉🎉🥳 nature.com/articles/s4158… LEMUR is a tool to analyze multi-condition single-cell data and model differential expression as a continuous function of the cell-state space. Some highlights⬇️

Excited to share my PhD findings! We discovered that air #pollution alters the biofilm formation of #bee gut commensal Snodgrassella and disrupts the bumblebee gut #microbiome - highlighting new environmental impacts on pollinators and microbial ecology. nature.com/articles/s4152…

Super excited to share our new study from the Jason Buenrostro Lab in nature! We developed a computational method for tracking transcription factor and nucleosome binding using single-cell ATAC-seq and deep learning. Paper: nature.com/articles/s4158…