🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

It's been out a while, but... Our recent work on His-ADPr utilizing Solid Phase synthesis: onlinelibrary.wiley.com/doi/full/10.10… Building on the four-of-a-kind predecessor 👇

And now for our most recent work: ADPr analogues rising up against the coronavirus! In a very fruitful collaboration with the Ivan Ahel Lab . Replacing Adeno- with Remde- by swapping out Adenosine for the Remdesivir metabolite GS-441524! And much more ;-)

Outstanding scientists elected to EMBO Membership: in EMBO’s 60th anniversary year, 100 new members and 20 associate members join the community embo.org/press-releases…

An exciting Post-Doc position is available in the Gromak lab at the Dunn_School (now @DunnSchool.bsky.social), University of Oxford, to study R-loop biology. Deadline 22 July. 👇🏻 my.corehr.com/pls/uoxrecruit…

Our new paper demonstrating reversible ubiquitylation of DNA and RNA: embopress.org/doi/full/10.10…

New job opportunity 📢 Associate professor, immunity/inflammation/infection (defined broadly) especially welcome Come and join a great community of supportive colleagues! Deadline 25 October, please spread the word path.ox.ac.uk/vacancy/associ…

Here is the first paper out of my lab 🥳 A deep dive into a new class of macrodomains specific to bacterial and fungal pathogens. #AMR I'm super greatful to Antonio Ariza Ivan Ahel Lab Filippov ADPr Lab and the other amazing people that help on this project! jbc.org/article/S0021-…

If you are interested in the regulation of interplay between ADP-ribosylation and lipoylation, check our collaborative paper. Congratulations to all authors, especially to our former postdoc Johannes for his first paper as an independent group leader! jbc.org/article/S0021-…

Our new paper describing how tyrosine-linked ADP-ribosylation signalling is reversed. Big thanks to our collaborators JGM_Rack, Filippov ADPr Lab and The Matic Lab. jbc.org/article/S0021-…

Our team in Orléans (France) is looking for a new postdoc, to work closely with a research associate, Ibtissam Talhaoui, on a project focused on potential SUMO E3 ligases targeting the nucleosome. The details here: emploi.cnrs.fr/Offres/CDD/UPR…

We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home/

We're in the news. 😊 JGM_Rack Ivan Ahel Lab Filippov ADPr Lab Phys.org phys.org/news/2024-10-s… doi.org/10.1016/j.jbc.…

Our new paper in collaboration with Luca Palazzo laboratory: authors.elsevier.com/sd/article/S14…

Our laboratory is looking for a postdoc with expertise in protein biochemistry and structural biology to work on novel pathways regulated by ADP-ribosylation of nucleic acids. Please RT.

Potential PhD students interested to work in our laboratory are welcome to apply through the ILESLA programme

I'm excited to share the final version of this story published in The EMBO Journal Check it out! embopress.org/doi/full/10.10…

Call me a #ubiquitin geek, but this is genuinely one of the most exciting findings in recent years. Only came across Ub—ADPr a few years back with some pioneering Ivan Ahel Lab papers. New field emerging here, folks!

Our discovery of reversing enzymes for RNA ADP-ribosylation reveals a possible defence protein module against toxic attack pubmed.ncbi.nlm.nih.gov/39970281/

Our new paper describing the RNF114 protein as a reader of dual hydrid modification composed of ADP-ribose and ubiquitin (ADPr-Ub) we discovered a few years ago (collaboration with the lab of Gerbrand van der Heden van Noort) biorxiv.org/content/10.110…