A single genomic change may have given modern humans an advantage over more ancient contemporaries like Neanderthals by enabling increased neocortical neurogenesis, a 2022 Science study found. Learn more in this #SciencePerspective: scim.ag/8kW #ScienceMagArchives

Fluorogenic sensing of amorphous aggregates, amyloid fibers, and chaperone activity via a near-infrared aggregation-induced emission-active probe, exciting work featuring Zoe Chen (med.upenn.edu/shorterlab/Peo…): onlinelibrary.wiley.com/doi/10.1002/ag…

Live-cell visualization of tau aggregation in human neurons 🤩 nature.com/articles/s4200…

Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia. Congrats Dave Attwell, Nils Korte and team! 🤩 nature.com/articles/s4159…

Extracellular vesicle-mediated trafficking of molecular cues during human brain development - congratulations Silvia ⁦@silvianeurompi⁩ and the all team 🥳 cell.com/cell-reports/f…

🧪A team of researchers, led by Helen Farrants & Eric Schreiter, developed a new way for engineered protein biosensors & bright, fluorescent Janelia Fluor dyes to work together, creating a new biosensor for measuring physiological signals in live animals.➡️janelia.org/news/new-biose…

We're excited for our latest work published in @Neuron! We explored the impact of Alzheimer's risk factors APOE4 and TREM2-R47H in a tauopathy mouse model, revealing elevated microglial cGAS-STING signaling and senescence in females with both risk factors. cell.com/neuron/fulltex…

#newPI lab website up! We are the Glial Epigenetics Lab #glia. Hiring at all levels! Please reach out if you are interested in glia, epigenetics, or sense of smell. Added perk of living close to the mountains! Email - [email protected] debosardarlab.org

CRISPR–Cas9 screens reveal regulators of ageing in neural stem cells | Nature nature.com/articles/s4158…

Why are some neurons more selective than others? We report now in nature how calcium permeable-AMPA receptors in PV neurons make them less selective to sensory features nature.com/articles/s4158… Long live the geniuses behind this🧠🔍juhyun.kim Thomas Hainmueller @rhuganir

SFN oster right now T11! Meenakshi Asokan presenting gorgeous NPX recordings for weeks in females mPFC tracking neurons across estrogenic states. Very different network properties in high and low estrogen states

Cell-cycle-dependent mRNA localization in P-bodies: cell.com/molecular-cell…

❤️😍😍

Somatic mosaicism in schizophrenia brains reveals prenatal mutational processes | Science science.org/doi/10.1126/sc…

😍

😍

❤️

Legendary Creation by Ustad Zakir Hussain - The Legend of India 🙏 youtube.com/shorts/gVtkrmz… via YouTube

Cellpose3: one-click image restoration for improved cellular segmentation Carsen Stringer & Marius Pachitariu nature.com/articles/s4159…

Excited to share our new paper in Nature! 'Transcriptomic neuron types vary topographically in function and morphology' explores how neurons in the zebrafish optic tectum exhibit diverse functions and shapes despite similar transcriptional profiles. rdcu.be/d9GVM