Researchers identify immune system related genes (HLA alleles) linked with brain cancer risk in the population and patient outcomes. May start to answer the question why patients get brain tumors. academic.oup.com/neuro-oncology… Gary Kohanbash Costas Hadjipanayis UPMC Physician Resources SNO

.Journal for ImmunoTherapy of Cancer article explores recent findings and provides perspective on the complexity of how some immunotherapy may be effective for melanoma brain metastases. jitc.bmj.com/content/13/3/e… Gary Kohanbash Stephen C. Frederico 🧠👨🏻‍⚕️ UPMC Hillman Cancer Center

Researchers Predict Paradigm Shift in the Analysis of TILs in Pediatric Brain Tumors insideprecisionmedicine.com/topics/oncolog… via Inside Precision Medicine

Researchers Predict Paradigm Shift in the Analysis of TILs in Pediatric Brain Tumors insideprecisionmedicine.com/topics/oncolog… via Inside Precision Medicine

Fantastic study! Congratulations Itay, Gary and Ian!!!

Classifying childhood brain cancers by immune response may improve diagnostics and treatments, via EurekAlert!! eurekalert.org/news-releases/…

From TCRs to immunotherapy targets: detection of antigens in pediatric brain tumors acir.org/weekly-digests…

Congrats Gary et al. Pitt Neurosurgery POSTN is an extracellular matrix protein strongly associated with inflammatory 'mesenchymal' subtypes of GBM, and as we found over a decade ago, associated with peritumoral FLAIR signal in GBM. Even KD and overexpression recapitulated these MRI