New in Developmental Biology – Caspase3/7-dependent apoptosis promotes head development and neurogenesis in #Hydractinia metamorphosis. The constructive function of apoptosis. Well done Gabriel Krasovec (now with StemDevEvo) doi.org/10.1016/j.ydbi…

Living in Paris means lots of French cat visitors. We let them in, and when it's time to go, they say, "Le meow, le meow!" 🐾

Happy to share our new paper out today in The EMBO Journal. We identify SNRPB as a new regulator of ER proteostasis. We show that SNRPB is induced by the UPR and regulates the splicing of ERES proteins (e.g. Sec16A), thus controlling ER export of collagen-I. embopress.org/doi/full/10.10…

Exciting line up. I am looking forward to the talks. Do tune in on Sept 19 to know about a novel regulatory mechanism in the early secretory pathway necessary for maintaining homeostasis and compartmental identity.

Very excited to share our work on experimental & computational studies of membrane protein stability and trafficking among this fantastic lineup at the #MembraneTrafficking virtual seminars! Many thanks to the organizers. 🎉Join us this Fall!

Want a non genetically-encoded probe to label the Golgi in imaging and #STED super resolution experiments? Check out the clever trick from the The Matile Group! Happy to have been able to contribute to this pubs.acs.org/doi/10.1021/ja…

Interesting preprint from Shigeo Hayashi group! Gox-mediated autophagy, controls Drosophila cuticle nanopatterns by trafficking ER material directly to the plasma membrane. Endoplasmic reticulum patterns insect cuticle nanostructure biorxiv.org/content/10.110…

The big one is out 🎉 So over the moon to see our latest work with Steph Vassilopoulos published in Science Magazine. Check out how we reveal the unique architecture of clathrin-coated pits and endocytosis at the axon initial segment: science.org/doi/10.1126/sc…

Super cool to see our work with Christophe Leterrier out in Science Magazine 🥳 Check out how we combined super-resolution light microscopy and electron microscopy to visualize the endocytosis machinery at nanoscale resolution in neurons⚽️ science.org/doi/10.1126/sc…

The version for *posterity* is out Nucleic Acids Res! Congrats to lead authors Ana Monteagudo-Sánchez & Julien Richard Albert, our friend/collaborator Noordermeer lab 🇺🇦 & engineer extraordinaire Margherita Scarpa! Findings largely intact, but short 🧵 on changes since preprint academic.oup.com/nar/advance-ar…

This week on Wednesday (Aug 28) at 4:15 pm we have our next #GoenomiX seminar talk. Nikos Konstantinides from Institut Jacques Monod will talk about “Development and evolution of neuronal diversity”. Check details here: pad.gwdg.de/s/a_5KCo2cq

Great to finally see this online J Cell Science journals.biologists.com/jcs/article/13… I hope it is a great resource for everybody embarking in proximity labelling #masspec experiments! I promise all plasmids will be on Addgene in the next few weeks! Alexander Stockhammer Freund_Lab@FUB

What do French people call a lousy Thursday? A trajeudi

Interesting preprint with a model for NSF/Sec18 function from Axel Brunger's lab. Sec18 side-loading is essential for universal SNARE recycling across cellular contexts biorxiv.org/content/10.110…

Paper Alert! Our new work shows collagen IV variants act by collagen IV deficiency, hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease, a major cause of #stroke & #dementia eBioMedicine – The Lancet Discovery Science The Lancet UofG SCMH thelancet.com/journals/ebiom… a 🧵

Looking forward to visiting our neighbors/colleagues/friends Institut Jacques Monod to discuss the closest living relatives of animals!

Registration is now open for the Paris Cytoskeleton Day 2024! 👉 pcd2024.sciencesconf.org taking place Institut Jacques Monod on Nov 15th with amazing speakers!!!🤩 ‼️Deadline for abstracts Oct 20th.

I'm so happy to announce that I've been awarded an #ErcStG! We'll be studying the role of cytoplasmic bridges across the tree of life using stem cells and choanoflagellates!