Isaac Hilton
@isaacbhilton
Associate Professor @rice_bioe. Engineering the human genome, epigenome, and transcriptome to understand biology and improve human health.
ID: 959985070806269957
https://hiltonlab.rice.edu 04-02-2018 03:00:51
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excited to share COMET! A scalable CRISPR approach we (Caroline Wilson) developed to identify multidomain proteins that modulate transcription at specific endogenous genomic loci. Arc Institute @ucsf doi.org/10.1101/2024.1…
Our brilliant team of bioengineers continues to pave the way in immunotherapy with their new mathematical model. Discover more in the full story. 👨🔬💡 bit.ly/3YAQsyM Oleg Igoshin @jon_debonis
Congratulations to my Rice University Bioengineering colleague Omid Veiseh Omid Veiseh who is part of the 2024 National Academy of Inventors Class of Fellows! Very deserving recognition for one of the most innovative researchers I know! Proud to be a fellow fellow, hope to be there for your induction! 🏅
🚨NEW PUBLICATION ALERT🚨: In a paper out today in Science Magazine we describe a way to build synthetic phosphorylation circuits with customizable sense-and-response functions in human cells. Check it out at science.org/doi/10.1126/sc…. 🧵1/n
They grow up so fast! If you're in the Houston area go check out Kelsey Swingle's Rice University Bioengineering seminar next Thursday at noon, and also check out her recent study in nature on a placenta mRNA LNP platform to treat deadly pregnancy disorders (free access): rdcu.be/d3dm2
An amazing Rice University PhD recruiting event last night: “Night at the Museum”! Wow, nobody does it like Rice 👋🤚🦉 See y’all in August!
Innovation starts here! In our new podcast episode, host Maya Pomroy chats with Paul Cherukuri, Rice’s vice president of innovation & chief innovation officer, about fueling game-changing ideas & cementing Houston’s place as a leader in innovation. pod.fo/e/2b7993
Today at Cell Systems we report in back-to-back papers (!) led by Nat B. Wang 🧬🧑🏻🔬🏳️🌈 on how cell state potentiates the influence of individual transcription factors to drive cell-fate programming & how we used these insights to scale up production of motor neurons from primary
Fresh in Nature Biotechnology! We developed a synthetic biology tool for tracking gene transfer in microbial communities and applied it to study plasmid hosts in a wastewater microbiome. Awesome collab with Chappell Lab & Joff Silberg and incredible students. nature.com/articles/s4158…
Thrilled to see my digital art on the cover of Trends in Genetics! The two binary strings represent reverse-complementary DNA sequences (00=A, 01=C, 10=G, 11=T) and the connecting rectangles represent “embeddings” learned by DNA language models. Our article: doi.org/10.1016/j.tig.…
The Bioengineering faculty took a break during last Friday’s departmental retreat to tour the new research space in the Helix Park campus of Texas Medical Center !