We are looking for new colleagues - both PhD and PostDoc positions available! Exciting projects involving biochemistry, single-particle cryo-EM & tomography, and cell biology. Please spread the word and apply!

Over the moon about my postdoc work ⁦Science Magazine⁩ ! Ever wonder about how mammalian cells selectively degrade unwanted nuclear proteins without involving ubiquitination? Check out our paper on a non-canonical protein degradation mechanism! science.org/doi/10.1126/sc…

BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

For a fundamental discovery that has enormous impact on humanity

In vitro system for the initiation-elongation transition captures early events in RNA polymerase II transcription: ⁦Yumeng Zhan⁩, ⁦Christian Dienemann⁩ et al., ⁦Elisa Oberbeckmann⁩ et al. biorxiv.org/content/10.110…

Comparison of four transcription elongation factors reveals conserved regulatory mechanisms. New review by Ying Chen sciencedirect.com/science/articl…

Very happy to share the final version of our paper in Nature Genetics, in which we reconstitute chromatin domains and find that nucleosome positioning plays an important role in higher-order folding of chromatin: nature.com/articles/s4158…

Beautiful work on the transcription-DNA repair coupling puzzle

Nature research paper: Smoking changes adaptive immunity with persistent effects go.nature.com/3SD1K2t

We have open European Research Council (ERC)-funded post-doc positions to study #3Dgenome organization and #generegulation. We are looking for talented and motivated candidates, but prior experience in the field is not required. Please RT! mpinat.mpg.de/4627722/Aussch…

CDK7 kinase activity promotes Pol II promoter escape by facilitating initiation factor release. Congratulations⁩ ⁦Taras Velychko 🇺🇦⁩ et al. ⁦Michael Lidschreiber⁩! cell.com/molecular-cell…

Deadly kiss of polymerases: How Influenza polymerase cleaves capped nascent RNA from host Pol II to start its own transcription. Preprint from Alexander Rotsch et al. with Steven Cusack‘s lab EMBL Grenoble. biorxiv.org/content/10.110…