Congratulations Auria Biobank (Turku, Finland) for 10 years of storing precious samples and data and enabling fantastic research. Great seminar today, which concluded in a fun rap-video.

INTERVENE is featured in an article in Inside Precision Medicine, where Samuli Ripatti and Andrea Ganna Samuli Ripatti Andrea ganna were asked about AI-based prediction models. insideprecisionmedicine.com/topics/informa…

Helen Cooper (Helen Cooper) is the new communications officer for INTERVENE. She kicked off by talking to high-school students about genetics and polygenic risk scores.

Largest comparison of PGS methods so far also assesses variability across biobanks.

Great work by Remo Monti Christoph Lippert and others as part of intervene_eu consortium.

Take home message: Variability between biobanks > between methods

Check: …comparison.intervenegeneticscores.org

Our latest work comparing polygenic scoring methods in 5 biobanks and 16 traits. Huge thanks to all our collaborators at intervene_eu medrxiv.org/content/10.110…

Amazing #ashg2023 so far! I am presenting a poster on multi-ancestry PGS disease prediction today on behalf of intervene_eu. Come and find me at BP1595 (look for the reviewers' choice badge 🏵️ William Harvey Research Institute Genes & Health

Great talk from Kristi Läll on her PheMED analysis intervene_eu #ASHG2023

After great talks from Francesco Florindi, Sowmiya Moorthie & Suzette Delaloge, we subjected them to further questioning on whether and when PRS are ripe for the clinic. With INTERVENE's  Andrea ganna, and Elisabeth Widen moderating.

The INTERVENE 2023 Annual Meeting is underway in beautiful Rotterdam. Andrea Ganna opens the meeting with a highlight overview.

This has now been published. Congratulations to the intervene_eu team and particularly to sophiewharrie for the leadership 👏

academic.oup.com/bioinformatics…

Amit V. Khera Atlas Khan @eMERGENetwork_ daniel rosales This is a collaborative effort from Benjamin Wingfield Sam Lambert Laurent Gil Aoife McMahon Mike Inouye & more PGS Catalog Cambridge University @EMBLEBI Health Data Research UK (HDR UK) Baker Institute!

pgsc_calc is designed to integrate into analysis platforms, such as the forthcoming platform from intervene_eu!

Recently I presented our intervene_eu research on polygenic risk scores to German health minister Prof. Karl Lauterbach. Interested, he asked to take a picture 📸. He (and you) can now read about it in our new pre-print medrxiv.org/content/10.110…

This really cannot be emphasized enough. Great collaboration driven by brilliant young researchers!

Proud to announce the preprint of the intervene_eu flagship project! Using data on more than 1.3M individuals, we provide a PRS-based framework for country-, age-, and sex-specific estimates of the cumulative incidence for 18 high-burden diseases.

Thread by Brooke below 👇

Was a pleasure to be a part of it with Mónica Cano Abadía Melanie Goisauf sharing our knowledge and recent learnings EOSC-Life EuCanImage intervene_eu

It´s a wrap! Very inspiring analysts workshop with lots of new and great ideas! Thank you all - Arrivederci!

G´morning from sunny Siena! Second day of the Analysts workshop started with group discussions on machine learning for epidemiology & improving PRS and biomarker trajectories & utilizing available omics data.

During the 1st part of the day of the Analyst workshop several projects presented their current status and exciting prospects for the INTERVENE.

The 2nd INTERVENE Analyst meeting is about to start in Siena, Italy!

Great interdisciplinary work from the intervene_eu #ELSI team et al. on the complexities & challenges of AI-driven PRS use. Clearly much to be done in this area, with embedded ethics a central component of our work to implement PRS in clinical practice.

frontiersin.org/articles/10.33…