Aerosolised antibiotics in #ICU 💨 delivery to tracheobronchial tree? easy 💨 delivery to infected lung parenchyma? difficult 💨 clinical delivery of aerosolized ABTS 💨 how to address unmet clinical needs from a research standpoint Free to read #FOAMcc 🖇️ rdcu.be/datQH

🧫 Ventilator associated tracheobronchitis & pneumonia share same acquisition pattern: pathogen colonizes proximal & progresses to deeper airways = VAT, until local defences overwhelmed, alveolar damage & infection = VAP. Term "VA-LRTI" could simplify?? 🖇️ rdcu.be/dbONV

#PedsICU Cuidados Intensivos Pediátricos H. U. La Paz

#pedsicu

The transfusion dilemma Belen Calderon Llopis, MD, PhD Cuidados Intensivos Pediátricos H. U. La Paz #ESPNIC2023 ESPNIC #PedsICU

Infection, colonisation, sterile inflammation in critical illness? 🧫 current approaches to distinguishing 🧫 host–pathogen interactions 🧫 techniques to characterise host response 🧫 challenges/limitations of host‑response diagnostics #FOAMcc Intensive Care Medicine 🖇️rdcu.be/de6sw

🆕️⚡️🔥Propensity-score-weighted cohort 183 adults with CRE BSI 24 US hospitals Patients receiving short-courses of active therapy (7-10d) experienced similar odds of recurrent bacteremia or death within 30d as those receiving prolonged courses (14-21d) academic.oup.com/cid/article-ab…

Folks, tomorrow we’ll be announcing the NEW PEDIATRIC SEPSIS CRITERIA SCCM! A huge multinational and multidisciplinary effort, based on the largest data-driven effort of the kind (>3.6M peds encounters). Concurrent publications in JAMA! #sccm2024 #PedsICU #DataScience

Duration of antibiotic therapy among paediatricians: A national survey of current Clinical practice in Spain. sciencedirect.com/science/articl…

FUNDICU invasive fungal diseases in adults in #ICU consensus definitions by ESGCIP ESCMID Fungal Infection Study Group (EFISG) ESICM ECMM MSGERC ISAC ISHAM for 🍄invasive candidiasis 🍄invasive aspergillosis  in non-neutropenic pts w/o classical host factors 🖇️ bit.ly/3PAqqrJ

#pedsicu

🔥 Just published 🔥 IDSA 2024 Guideline Update on the Risk Assessment, Diagnostic Imaging, and Microbiological Evaluation of Complicated Intra-abdominal Infections in Adults, Children, and Pregnant People #idxposts idsociety.org/practice-guide…

🆕 Publicada nuestra experiencia en niños con ceftazidima-avibactam en infecciones multirresistentes complicadas o recurrentes. mdpi.com/2846382 #mdpiantibiotics a través de Antibiotics MDPI SEIP Sº Farmacia La Paz Cuidados Intensivos Pediátricos H. U. La Paz Microbiología Clínica La Paz 🦠 Pediatría, Infecciosas y Tropicales. H. La Paz ERN TransplantChild

Esta semana hemos disfrutado del 3️⃣ Curso de Instructores de Simulación 👶🏼 en UCI Pediátrica H. G. U. Gregorio Marañón Hemos contado con unos participantes fabulosos a los que les había picado el 🐛 de la #simulation y ahora están más que preparados para continuar desarrollándola Gracias a todos!! 👏🏼

Algorithm for evaluation of infections in cirrhosis Discontinuation of empiric antibiotics or narrowing to organism-specific antibiotics should be expedited to avoid unnecessary antibiotic exposure. doi.org/10.1097/HC9.00…

Proposed algorithm for the management of MBL-producing Enterobacterales Clinical Microbiology and Infection doi.org/10.1016/j.cmi.…

Enormous multidisciplinary work. Proud to be part of this team. This document addresses relevant issues related to the use of molecular syndromic panels on critically ill patients to assist in making management decisions. pubmed.ncbi.nlm.nih.gov/39736683/ Clínica Universidad de Navarra

🆕️🔥Suggested Dosing of Select Beta-lactam Agents for the Treatment of AMR GN Infections in Children The document serves as a companion document to IDSA AMR guidance to assist pediatric specialists with dosing β-lactam in Children w AMR infections academic.oup.com/jpids/article-…