We are excited to share our work at #AACR24 and our co-publication in Cancer Discovery Cancer Discovery! Huge thanks to the teams at Sanger, GSK, and Ideaya for their hard work and collaboration and to the CD editors for their support!

Our work 'Novel WRN Helicase Inhibitors Selectively Target Microsatellite Unstable Cancer Cells' is published today in Cancer Discovery (aacrjournals.org/cancerdiscover…). Using genetic tools, in 2019 Cancer Dependency Map Sanger and others reported WRN as a synthetic-lethal target in MSI cell line. 1/5

Just published with the #AACR24 presentation in the Novel Antitumor Agents session— Novel WRN Helicase Inhibitors Selectively Target Microsatellite Unstable Cancer Cells.
bit.ly/3VRrhYW
Gabriele Picco Mathew Garnett Garnett Lab Wellcome Sanger Institute AACR

Whether or not you're at the #AACR24 minisymposium on experimental and molecular therapeutics right now, read the hot-off-the press Cancer Discovery paper by speaker Gabriele Picco, Garnett Lab, and colleagues describing novel Werner helicase inhibitors👇🏼aacrjournals.org/cancerdiscover…

And so well-deserved! 👏🏻👏🏻👏🏻

Honored and privileged to be able to contribute my opinion on the role of senescent cells in tumorigenesis in this updated Hallmarks of Cancer piece for Cancer Discovery with this group of amazing investigators. Credit really goes to the pioneers in the field whose shoulders we stand on.

Don't miss this issue of Cancer Discovery including many thought-provoking #perspectives on the past discoveries and questions ahead that are shaping how we understand #cancer in its complexity.

Happy to have contributed to one of the pieces of this evolving puzzle👇🏻

IRB Barcelona

Very important funding resource info for #earlycareer #cancer researchers, courtesy of Denis Wirtz and colleagues 👇🏻

Such an important resource, in the current climate, for cancer research trainees: hats off to Denis Wirtz and colleagues! 👇🏻

Excited to see our phase 2 multicenter study of Tumor-Infiltrating Lymphocyte in Advanced #LungCancer Resistant to Immunotherapy in Cancer Discovery. #TIL #Celltherapy aacrjournals.org/cancerdiscover…

Check out this beautiful characterization of macrophages/macrophages niches in colon cancer by @MagdaMatusia and colleagues! 👇🏻

Here is the link to Cancer Discovery Online First: aacrjournals.org/cancerdiscover…

We have an exciting program, networking and many activities planned for our very first “Women in Leadership” workshop at #EACR2024 !

Come join us in Rotterdam this June!

#WomeninScience #WomenInSTEM
EACR

The Spatial Human #Macrophage Map is finally online in Cancer Discovery! We show how phenotypically distinct macrophage populations occupy spatially segregated tissue #niches , with #IL4I1 and #SPP1 TAMs predicting opposite outcomes in colon cancer!

Come out and join us! The rain is holding off! #orioles Johns Hopkins BMB Johns Hopkins Kimmel Cancer Center !!

The amazing Ashi_W and her Johns Hopkins Bloomberg School of Public Health colleagues dispensing advice and merch about #melanoma and safety precautions for Baltimore Orioles opening day #prevention

Kevin Burton Cancer Research entering the normal human tissue matrix with Andreas Lund Indiana University at National Cancer Institute Chan Zuckerberg Initiative Young Investigators Atlas meeting

Sandra San Miguel NCI Disparities is providing so much training/funding info for trainees/ #earlycareerresearchers : check them (and the different databases maintained by Denis Wirtz et al) out 👇🏻

The The Fulbright Program is crucial for establishing important collaborations, as evidenced by the recent work described by Clayton Hayes and the team selection of the recent round of Cancer Grand Challenges applications

Going to highlight the various consortia at the NIH Chan Zuckerberg Initiative Junior Investigators Atlas Builders 2024 meeting: Clayton Hayes Johns Hopkins Kimmel Cancer Center talks about applying ‘omic approaches to samples to understand racial/ethnic differences in prostate and breast cancer