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#ICYMI: Combining magnetically isolated CD45 cells with serum maintains intact drug responsiveness for ELISpot analysis in clinical trials ow.ly/WQxx50VbTyV

#ICYMI: Comparison of immune responses to #RSV in infancy, childhood, and adulthood using an in vitro model of human respiratory infection. #immunology ow.ly/hKct50VbTEx

ImmunoHorizons New in IH: Regulatory #Tcells in the tumor microenvironment display a unique chromatin accessibility profile. #openaccess #immunology ow.ly/ct5h50Vj97g

New in IH: Regulatory #Tcells in the tumor microenvironment display a unique chromatin accessibility profile. #openaccess #immunology ow.ly/ct5h50Vj97g

New in IH: Deficiency of H3K27 histone demethylase UTX in T cells blunts allergic sensitization and anaphylaxis to peanut. #openaccess #immunology ow.ly/O5gf50Vj9a5

ICYMI: Defining a novel DYRK1A-gp130/IL-6R-pSTAT axis that regulates Th17 differentiation. #openaccess #immunology ow.ly/rlc150Vj9kX

#ICYMI: CD209d/e promotes inflammation and lung injury during influenza virus infection. #openaccess #immunology academic.oup.com/immunohorizons…

ICYMI: Comparison of B Cell Variable Region Gene Segment Characteristics in Neuro-autoantibodies ow.ly/7Sa450Vj9uo

The JI invites submissions of clinical and human immunology research papers for an upcoming special collection. The editors seek manuscripts presenting novel findings that derive from studying human subjects and/or human tissues. For more information 👉 ow.ly/4uI950VqswR

#ICYMI: A vaccine candidate derived from highly conserved regions of the SARS-CoV-2 spike, nucleocapsid, and membrane proteins elicited successful immune responses in hamsters. Vaccine candidates like this are key for evolving virus variants. Read more: ow.ly/ePEA50VrCGX.

No #AprilFools – Early Bird registration ends on April 4! Meet colleagues like Pamela Diaz-Saldana, Ph.D. candidate, who looks forward to the connection, collaboration and cutting-edge #immunology research at #IMMUNOLOGY2025™. Register now: ow.ly/sREq50VsgQR.

#ICYMI: Circadian rhythms determined the magnitude of inflammatory cytokines and chemokines of macrophages internalizing Plasmodium spp.–infected RBCs, revealing a key to understanding the severity of disease in #malaria patients. ow.ly/2NM850VrCJv

New in ImmunoHorizons! Spinal cord injury induces infection and inflammation of rectal tissues containing gut-associated lymphoid tissue, leading to gut dysbiosis, neurogenic bowel dysfunction, and systemic diseases. See more: ow.ly/6Uuz50VrCQu.

New clinical data evaluated MK-6194, an interleukin-2 mutein that selectively activates Tregs, for safety, pharmacokinetics, immunogenicity, and pharmacodynamics. The findings support MK-6194 as a potential treatment for #autoimmune disorders. Read now: ow.ly/XX8350VvOUb

Newly Published! Data demonstrated that natural genetic variation controls host survival and transcriptional reprogramming during endotoxemia, suggesting possibilities for prediction of sepsis risk and personalized therapeutic interventions. Learn more: ow.ly/z84050VvPh5

Because Tregs limit the anti-tumor immune response, researchers analyzed the chromatin accessibility of Tregs in the murine tumor microenvironment to identify tumor-specific accessible peaks and see if they changed over time. Read the findings: ow.ly/lg5250VvPoq.

Data revealed that UTX expression (histone H3 lysine 27 demethylase) in #Tcells impacted the production of antigen-specific #antibody responses required for allergic sensitization and anaphylaxis, suggesting a role in regulating #peanutallergy. Learn more: ow.ly/R84550VvPrA

Maresin-1 has strong anti-inflammatory action, which may present challenges in wound healing, as shown by new data that found wound healing was delayed in maresin–1–treated mouse skin due to a decrease in tumor necrosis factor alpha. Read more: ow.ly/Osqo50VEMGT

ImmunoHorizons invites you to submit a manuscript for a special series on #autoimmunity that will showcase cutting-edge research and advances, offering an opportunity to share impactful findings. Learn more and submit today: ow.ly/WM4c50VEMJ6

ImmunoHorizons (IH) is a fully open access peer-reviewed journal committed to advancing the knowledge of immunology and immunology education. Learn more about why you should publish in ImmunoHorizons today: ow.ly/BgxV50VEMTY.