🧬 New paper Nature Communications in collaboration with international partners 🇨🇭🇩🇪🇭🇺 & 🇵🇱 Michal Jasinski 🌱 A key residue of the extracellular gate provides quality control contributing to ABCG substrate specificity 📖 nature.com/articles/s4146… #PlantBiology #ABCTransporters #ICHBPAN

Today we host Prof. Wojciech Gawelda. He gives a talk on Research opportunities for studying bio-chemical dynamics with X-ray free electron lasers. The #XFEL infrastructure is now available for researchers Instytut Chemii Bioorganicznej PAN thanks to agreement with IF PAN & funding Ministerstwo Nauki i Szkolnictwa Wyższego

🦠 New paper Instytut Chemii Bioorganicznej PAN by D. Lorent, R. Nowak, M. Gazecka, P. Zmora and E. Lenartowicz Onyekaa: The effect of the PKR inhibitor, 2-aminopurine, on the replication of influenza A virus, and segment 8 mRNA splicing 🔗 Read: degruyterbrill.com/document/doi/1… #Virology #Influenza #mRNAsplicing

BIO2025 – Extended deadline for registration and submission of abstracts at a reduced price until June 30, 2025. bio2025.pl

Gratulujemy laureatom! Szczególnie dr Annie Kotowskiej-Zimmer z Zakładu Inżynierii Genomowej Instytut Chemii Bioorganicznej PAN. W projekcie #LIDER Pani Doktor będzie badała zastosowanie sztucznych #miRNA do allelo-selektywnej terapii ataksji rdzeniowo-móżdżkowych spowodowanych ekspansją powtórzeń #CAG.👏

This review from Instytut Chemii Bioorganicznej PAN presents the molecular pathologies of RNase-associated hereditary #MendelianDiseases, with updated information on disease models, and highlights the significance and advantages of employing #ModelOrganisms to study specific Mendelian disorders.

🌿New paper Instytut Chemii Bioorganicznej PAN: Overexpression of #UGPase and SPP genes in #Nicotiana tabacum boosts #biomass and speeds up development by enhancing #sucrose synthesis efficiency. 🔬A step forward in #plant #biotechnology and crop yield optimization. 📖 Read more: biotechnologia-journal.org/Overexpression…

Our study just published! 🔬🧬🧠🧐 We investigated initial deregulated molecular pathways in Huntington's disease in developing neurons. Instytut Chemii Bioorganicznej PAN cellandbioscience.biomedcentral.com/articles/10.11…

🚀 New review from our researchers Molecular Therapy ! K. Maziec, A. Baliga-Gil, and E. Kierzek explore delivery strategies for RNA-targeting therapeutics & mRNA vaccines against IAV, SARS-CoV-2, and #RSV. 🔬 A must-read for RNA-based #antiviral #innovation! 📖sciencedirect.com/science/articl…

Interested in: membrane transport, ABC proteins, in silico molecular modeling ? Join us in the project: Learning from plants: Identification of internal and external factors determining the polarity of ABC transporters in higher plants portal.ichb.pl/wp-content/upl…

ICHB PAN oraz Pałac w Turwi zapraszają na cykl wykładów „Nauka na Szlaku”. Pierwszy wykład z serii „#Wielkopolska Kolebką Polskiej Państwowości” pt. „Jak powstało Państwo Piastów?” odbędzie się w Miejskiej Bibliotece Publicznej w Kościanie, 30 lipca 2025 r. o godzinie 17:00.

New review from A.Dutta, A.Zaremba & P.Jackowiak Genes & Diseases Journal 👉Ribonucleases in Mendelian disease: Characterization and insight from model organisms - explores how #RNase mutations drive #genetic disorders and how model organisms help us decode them 🔗 sciencedirect.com/science/articl…

Na portalu Polska Akademia Nauk ACADEMIA przeczytać można o nowej strategii rozwoju nauki w Polsce, opracowanej przez zespół, któremu przewodniczy prof. Marek Figlerowicz z Instytutu Chemii Bioorganicznej PAN. 👉academia.pan.pl/nauka-dla-przy…

🔬 New Scientific Reports from W. Kotkowiak, N. Bartyś & A. Pasternak Instytut Chemii Bioorganicznej PAN ❗️ "Towards improved anticancer properties of the G-quadruplex-forming T40231 aptamer through increased flexibility of nucleoside residues" #CancerResearch #Aptamers #GQuadruplex 📰nature.com/articles/s4159…

🧠New study Instytut Chemii Bioorganicznej PAN in Cell & Bioscience OACellBiology sheds light on early #HuntingtonsDisease mechanisms! #neuroscience #RNA #HDresearch #HTT 📖cellandbioscience.biomedcentral.com/articles/10.11…

🚀 New publication alert! Our latest paper Trends in Biochemical Sciences explores the expanding roles of AID/APOBEC deaminases beyond DNA/RNA editing—impacting immunity, genome stability & more! 🧬 🔗 Read more: sciencedirect.com/science/articl… #AID #APOBEC #DNAEditing #RNAEditing #Biochemistry

We were delighted to host colleagues from Institute of Biotechnology in Poznań. Thank you for inspiring discussions. Looking forward to the next steps together. The visit was made possible thanks to collaboration between Polska Akademia Nauk and Czech Academy of Sciences 🤝

🚀 New paper in Nature Communications! Dr. Volodymyr Cherkas Instytut Chemii Bioorganicznej PAN co-author in a study on #GraMOS – a graphene-based platform for light-driven, non-invasive neural control. Article in international #research cooperation 🇵🇱🇺🇦🇺🇸🇧🇷 Read more 👉👇nature.com/articles/s4146…

🧪 New paper ChemMedChem by Natalia Bartyś, Anna Pasternak, Jolanta Lisowiec-Wąchnicka Instytut Chemii Bioorganicznej PAN👉 Modified Nucleotides in Bifunctional Antisense Oligonucleotides: Exploring their Anticancer Potential …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cm… #RNAtherapeutics #CancerResearch #MolecularMedicine

New report by Klonowska et al. 🇵🇱🇺🇸Genetics in Medicine 👉 TSC angiofibroma and ungual fibroma have different mutation signatures, with recurrent mutations in KMT2C #TSC #tumor sciencedirect.com/science/articl…