CurQD nutraceutical improves #urgency in active UC: A Post-hoc analysis of PCB-RCT now published in Journal of Crohn's and Colitis With caveat of not specifically validated for this outcome, the assessment of urgency is another benefit of SCCAI score. Y-ECCO pubmed.ncbi.nlm.nih.gov/39279191/ Note my COI

Congratulation to Millie Long Dr Dermot McGovern and Jordan Axelrad, MD, MPH. Thank you for your transformative contributions to the field of #IBD. Question: Will Dr Dermot McGovern wear a Liverpool FC jersey in the video?

Congrats to Adam Faye MD MS who has been awarded a #NIH/#NIA K76 Paul B. Beeson Emerging Leader Career Development Award in Aging, to study the optimal preop care of older adults with #IBD The National Institute on Aging (NIA) NIH NYU Grossman School of Medicine #FutureofMedicine

So 🙏 for all of my mentors & support along the way Aasma Shaukat MD MPH John Dodson #JoshChodosh #MaraDeMarco Dorry Segev Victoria Vaughan Dickson, PhD RN FAHA, FHFSA, FAAN Benjamin Lebwohl #ChinHur Josef Coresh ACG Crohn's & Colitis Foundation The National Institute on Aging (NIA) Clin-STAR Coordinating Center NYU Grossman School of Medicine

Today LiveSMART completed enrollment It is a trial to prevent falls and hepatic encephalopathy in people with cirrhosis It’s a controlled trial of Lactulose and tai-chi in Michigan, Texas, and Pennsylvania It has been a joy and a privilege

We are partnering with Crohn's & Colitis Foundation & many other orgs in the community to conduct an IBD Prevention Survey 🫶🏽  If you or a family member has #IBD, we want to hear your opinions re preventing IBD 👌🏽 Please participate in a quick survey here: bit.ly/IBDPrevention ✍🏽

Congrats to Adam Faye MD MS! Looking forward to see how you move the field of #IBD in the older adult forward 🙌

#MondayNightIBD AbbVie Takeda JanssenUS Jason Schairer Neilanjan Nandi, MD, FACP Sowmya Sharma Chris Lamb Patriciakaazan Beatriz Gros Joseph Sleiman, MD ignacio catalan Parambir Dulai Seb 25F w mod #panUC in endo remission on ADAL. 1 yr later: painful palpable #purpura ankle + foot (📸👆🏽). Bx: #LeukocytoclasticVasculitis-Refractory to prednisone. ADAL stopped as ?trigger of LV, started VDZ. One LV spot -> painful #ulcer, red-purple borders (📸👆🏽) What’s next?

Aline Charabaty, MD, FACG, AGAF #MondayNightIBD AbbVie Takeda JanssenUS Jason Schairer Neilanjan Nandi, MD, FACP Sowmya Sharma Chris Lamb Patriciakaazan Beatriz Gros Joseph Sleiman, MD ignacio catalan Parambir Dulai Seb Angus Worthing MD Steven Chen 陳持威, MD, MPH, MHPEd Dr. Lisa Iannattone Allison Larson, MD Ethan Craig Adam L. Booth, MD Jami Kinnucan, MD, FACG, AGAF, FCCF Edward Loftus Nisha Loganantharaj Jonny Blackwell David Choi, PharmD B. Evana Ghassemi, PHARMD, BCACP, BCPS Sang Hyoung Park Shrinivas Bishu John Ding MD PhD I'll bite 🫣 Tho classically LCV 🚫follow IBD activity most cases I have seen have, interestingly. If on island with just 💊💉, I'd try upa - broad and quick on/off if we decide to go a different route... ...with the multi-d team I would really want! 🙏for derm&rheum colleagues

Genetics research can play a significant role in reducing health disparities. ⭐️We're excited to share our latest manuscript on the pharmacogenetics of IBD, focusing on the presence of TPMT, NUDT15, and HLA-DQA1*05 in Hispanic patients⭐️ authors.elsevier.com/a/1jq315UiFSkm… 🧵

CA19-9... When to order, how to interpret. Expert review - FREE at SMART-MD Journal of Precision Medicine. (retweet to your colleagues). smart-md.org/index.php/jpm/… David C Whitcomb MD PhD PanCAN UPMC Pitt Division of GI, Hepatology & Nutrition National Pancreas Foundation Shrinivas Bishu Derek O'Reilly Jin He

I feel fortunate 🙏🏻🤩

45% stop draining, 22% of fistulas close with 45 mg induction. Rates fall off with lower-dose maintenance. Is this a durability problem (do we need a mechanical intervention)? Or is this a dose problem for fistulas? TBD if fistulizing Crohn's may need extended 45 mg Upa #IBD

Encouraging results in post-hoc analysis of Upa in CD perianal fistulas. Yet bewildering how 20yrs later, IFX ACCENT2 trial is still the only pharmaceutical RCT in perianal dis!!. In essence this makes all other biologics/SM we give to these pts to be somewhat off-label...

Colorectal neoplasia surveillance intervals in IBD. - high-definition white light colonoscopy ✅ - good bowel preparation✅

Interesting study TLA1 in UC NEJM Why? new MOA, looks good and all that.... ▶️Deltas for Endo Remission > 20% this is the interesting bit. ▶️ they tried to identify people likely to respond to TLA1 BEFORE using a blood test based on SNPs (Fig 1 vs 3) nejm.org/doi/full/10.10…

Shrinivas Bishu NEJM The wave of the future - precision medicine! Can't wait til we have more of these tools in our arsenal to better guide best treatment options for our patients.

Shrinivas Bishu NEJM Sound science as evidenced by the fact that it took over a decade to engineer the antibody based on science from GWAS. A great paper on the Cytokine network and pathway for IBD from Nick Powell group shows TL1A to be an important upstream regulator.

Shrinivas Bishu Robert Battat MD NEJM The deltas did remind me of mongersen as well. Let's continue to be hopeful!