We decided to readvertise our exciting paper 'Cryptic mitochondrial ageing coincides with mid-late life and is pathophysiologically informative in single cells across tissues and species' 1/6 biorxiv.org/content/10.110…

Our latest paper is out today Molecular Cell! Led by a Alberto Hernandez-Armendariz and with important contributions from Andela Saric & @EllenbergLab! We show how chromosomes shift from being repulsive to becoming attractive during mitosis. Read all about it here: cell.com/molecular-cell…

Chromatin scientists, want to reorganize genomic loci as you wish? Out today in Cell--We made a tool that uses surface tension of engineered condensates to reposition DNA loci across microns of space in living cells in just a few minutes: VECTOR cell.com/cell/abstract/…

Online Now: Genome access is transcription factor-specific and defined by nucleosome position dlvr.it/TCTjzp

My favourite discovery ever has just come online. Can I please tell you about some seriously wacky molecular biology? The story starts with a reverse transcriptase that SOMEHOW defends bacteria from viruses. (👇 I recommend sound ON for the video 🎹) 1/

‼️Join us for the inaugural France-BioImaging Research Infrastructure Mechanobiology Working Group meeting on December 2-3, 2024 at CBI Toulouse and LAAS-CNRS in Toulouse! Registration (free!) and preliminary programme: france-bioimaging.org/announcement/j…

Woohoo! "A guide to single particle tracking" is now online! Together with François Simon & @S_vanTeeffelen, we share our thoughts on going beyond MSD analysis in Nature Reviews Methods Primers. doi.org/10.1038/s43586… Free read link: rdcu.be/dTKHd

Fantastic work from Laure Le Blanc's PhD, and a great collaboration with THE DUMENIL LAB and Daria Bonazzi! Bacteria get more crowded under confinement, decreasing biosynthesis and growth. But they still divide and become extra small! Check out to see how they perform under pressure

How do cells response to withdrawal of amino acids? It depends on the amino acid. ◼️Lysine withdrawal causes immediate cell-cycle stalling while the withdrawal of other amino acids allow for completion of additional cell cycles.

Timescales in Cell Biology

This paper highlights how error bars are often misunderstood, especially regarding statistical significance. Let's explore the key points to clarify these misconceptions. #Statistics #DataScience #Research #OpenScience nature.com/articles/nmeth…

Latest work from our group @Esoftbio National Centre for Biological Sciences, led by Sree Sreepadmanabh M, is out today in Nature Communications! In colab with @DeepaAgashe Christina Kurzthaler we report that the physical confinement acts as a selective pressure on bacterial growth in 3D! [1/16] tinyurl.com/mvbdm3ue

Metabolism and epigenetics sync up! 🌀 Histone acetylation not only activates genes but also acts as an acetate reservoir. #Metabolism #Epigenetics #HistoneAcetylation. Thank you Kirmizis Lab! More details Trends in Biochemical Sciences authors.elsevier.com/a/1k3PJ3S6GfQa…

Cell-cycle-dependent mRNA localization in P-bodies dlvr.it/TG5Fyd

"One email at a time, one informational interview after another, I became comfortable, confident, and strategic in building my network of mentors." One mentor isn’t enough, writes Erika Moore in this #ScienceWorkingLife essay from 2021. bit.ly/48iBjGZ

Our paper is finally out! We discussed how the Collagen signalling and ECM stiffness could regulate multipotency of glandular epithelia! Thanks to Cedric Blanpain for supervising this amazing project and thanks to AlessiaCent and Chen Jiang :) nature.com/articles/s4146…

How to "program" living cells.🧫 In 2000, physicists ( ElowitzLab) made bacteria blink on-and-off every 150 minutes. Their experiment, which blended mathematics and wet-lab methods, launched the field of synthetic biology. Learn how they did it in my first interactive story.

🚨🚨Please RT! 📢📢 Still time to submit short talk abstract for EdinPBS2025! Five themes this year: · Mechanobiology · Protein pattern formation · 4D Genome · Stochastic biology · Biohydrodynamics bit.ly/EdinPBS2025

An elegant model: - TF binding events on nucleosome-free DNA are independent. - Yet, the activation domains of TFs recruit cofactors that destabilize nucleosomes, resulting in cooperative TF binding. - Average TF occupancy linearly determines promoter activity