🔥🚨🔥 GOAL Trial kicks a goal! NEJM RHD affects >40.5 mil worldwide & results in 306,000 deaths/year. Echo screening detects early, latent RHD. Whether secondary antibiotic prophylaxis prevents progression of latent RHD was unknown. NOT ANYMORE!!! nej.md/3CcZFzY

🔥 The #StrepA Octoplex is here! 🐙 Tiny beads, tiny sample volumes, high throughput, huge results! ⁦Alana Whitcombe⁩ ⁦Nikki Moreland⁩ 🧪 👩‍🔬 pubmed.ncbi.nlm.nih.gov/34801540/

MCRI clinician-scientist Josh Osowicki tells us how he is using his @NHMRC Investigator Grant to advance Australian human challenge trials for priority pathogens. Watch here: vimeo.com/622874878 NHMRC_grants #humanchallengemodel #strepa #tropicaldisease

📢 Want to join the team? Be part of the world-leading Murdoch Children's Research Institute (MCRI) ID Research Group + support the #InfectiousDiseases Unit The Royal Children's Hospital, Melbourne. Research Officer 👉 bit.ly/3HZzTTo Research Assistant 👉 bit.ly/3KkZ6cL #BRACEtrial #BCGvaccine #COVID19 UniMelb MDHS

Congrats to Jeremy et al for this effort out of #CHIVAS, defining an immune signature (or correlate? 🤔) of infection for experimental #StrepA pharyngitis. And given we assume most healthy adults have self-limiting infections.....

Congrats to octamum (sorry!) Alana Whitcombe and Nikki Moreland et al for this excellent work, moving closer to an #ARF diagnostic assay 🐙

Please re-tweet! We are looking for a research officer to help us probe the function of glycosylation in bacterial systems. If you have experience with creating CRISPRi libraries and want to learn how to do proteomics come join the team! jobs.unimelb.edu.au/caw/en/job/908…

It has been an incredibly impressive and stimulating week, hearing the latest in #StrepA science at #lisssd2022 and #savac and hearing the boss sing #ABBA #kareoke Josh Osowicki Alana Whitcombe Reuben McGregor Nikki Moreland

Murdoch Children’s Prof Andrew Steer said the information collected will help inform how a #vaccine could be used to prevent a wide range of illnesses caused by #StrepA including sore throats, septicaemia, rheumatic heart disease and kidney disease. @CCCH_AU Jonathan Carapetis

MCRI's A/Prof Andrew Steer talks to Sarah Booth Herald Sun about the importance of sore throat research & how a better understanding of this bacterial infection is an important step in our efforts to eventually develop a vaccine. #childhealth #sorethroat #research #vaccine

Our study investigates how many children get sore throats, the body’s natural protective, immune response to Strep A sore throat and the types of #StrepA bacteria in our community throughout the year. A critical step towards developing a #StrepA vaccine asavi.org.au/sore-throat-st…

ASAVI (Strep A Vaccine) is running a wonderful & very important #StrepA sore throat surveillance study. Get involved! Murdoch Children's Research Institute (MCRI) telethonkids instagram.com/p/Cj4l0TbpaIf/

We’re hiring! 2-yr postdoc position at Murdoch Children's Research Institute (MCRI) using cutting-edge stem cell models and CRISPR screens to identify new treatments for respiratory infections 🫁 Any questions please reach out! Retweets appreciated career10.successfactors.com/sfcareer/jobre…

Prof Andrew Steer recently spoke to 7NEWS Australia about a recent spike in invasive Group A #Streptococcus (iGAS). Prof Steer has said the uptick of #iGAS #infections was a matter of "being alert but not alarmed" & urged parents to look out for symptoms. 7news.com.au/news/public-he…

Very excited to share our perspective on the current status of #correlatesofprotection for #StrepA just out in npj Journals nature.com/articles/s4154… S Sriskandan Alma F

MALICE IN CHAINS: “#StrepA was bad before the pandemic, is bad now, and will remain bad until we have a vaccine to reduce the enormous public health burden of life-threatening fast (iGAS) and slow (RHD) streptococcal diseases.” academic.oup.com/jid/advance-ar…

We're hiring! We're looking for two research assistants to join our Tropical Diseases group Murdoch Children's Research Institute (MCRI) working on #StrepA infection, immunity and vaccine research. career10.successfactors.com/sfcareer/jobre… Please share 🙏

We looked at the promiscuous genetic relationships between families of important #strepA virulence factors. Those networks have more splits than a yoga studio!

How much do you know about strep A infections? Watch to find out what signs point to a more severe case and when you should seek medical attention for your child.

Murdoch Children's researchers have secured prestigious US NIH grants worth a combined $11.8 million to advance #research into how #children’s #immunesystems respond to #StrepA infection & to trial treatment for #rheumaticheartdisease. Read more: mcri.edu.au/news/awards/fu…