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We’re excited to share our newest publication nature. With #scRNAseq we investigated 10 key #epigenetic regulators in #embryogenesis. Interesting early task for #Polycomb! Meissner lab MPI for Molecular Genetics & HSCRB /w Helene Kretzmer & Zachary D. Smith (1/13) nature.com/articles/s4158…

IT TRUE IT WILL BE GOOD RESOURCE! FOR PEOPLE TRYING TO FIGURE OUT HOW EPIGENOME WORK! ONLY NEEDED ONE PAPER TO SHOW PATH TO DATASET! NOW STOP WASTING MONEY AND FIGURE OUT MECHANISM! LIKE THIS MAYBE IS GOOD START: nature.com/articles/s4158…

Check out the newest publication from our lab! Congratulations Helene Kretzmer

Beautiful methylation pearl by Chuck Haggerty, Helene Kretzmer, Christina Riemenschneider, Abhishek Sampath Kumar, Alexandra Mattei, N Bailly, Raha Weigert & others on the "secret life" of Dnmt1 at #IAPs (as Chuck would say!). Congrats my friends! #MeissnerLab MPI for Molecular Genetics NatureStructMolBiol nature.com/articles/s4159…

🚨 #Job Alert! Computational #PhDposition (2/2): investigate the role of #epigenetics during development & regeneration, with cutting-edge HT technologies, incl #scRNAseq data at the #MeissnerLab Join us & apply for your #PhD in Berlin until July 21! 🔗 nature.com/naturecareers/…

🚨 #Job Alert! Computational #PhDposition (1/2): investigate #epigenomics in #cancer and development, using cutting-edge high-throughput technologies at the #MeissnerLab. Join us & apply for your #PhD in Berlin until July 21! 🔗 nature.com/naturecareers/…

🎉 SeqAn 3.1.0 released 🎉 We are happy and proud to announce a new release of the modern #CPP library for sequence analysis. Find out more about it at seqan.de/release/2021/1… or check it out right away github.com/seqan/seqan3/r…. Many thanks to all contributors and supporters.

Outstanding work by my brilliant colleagues who spent many months collecting and summarizing the key pieces to take us on a journey through the history of DNA methylation research. A must-read for anyone in the field and beyond.

Our review on new opportunities offered by single-cell technologies for investigating epigenetic regulation during mouse development is out today in Elsevier | ScienceDirect! A team effort with Helene Kretzmer and Alex Meissner MPI for Molecular Genetics. A short thread🧵 sciencedirect.com/science/articl…

Very excited to share the first piece of work from my PhD with Vahid Asimi Henri Niskanen Christina Riemenschneider Sara Hetzel Denes Hnisz out today in Nature Genetics nature.com/articles/s4158… MPI for Molecular Genetics

🚨!!!Preprint Alert!!!🚨 I am super-delighted to share our work co-led with Adriano Bolondi, PhD describing the discovery and characterization of a novel lncRNA, LNCSOX17, a key regulator of human definitive endoderm. #Meissner Lab MPI for Molecular Genetics. A🧵1/11 biorxiv.org/content/10.110…

Excited to share our work discovering a dynamic antagonism between #DNMT3B and #Polycomb that maintains the placental epigenome. Check out Raha Weigert thread for more details 👇👇 MPI for Molecular Genetics

☕️NEW ONLINE: Meissner, Smith & co show that an antagonistic relationship between DNA methyltransferase and Polycomb activity is globally responsible for the maintenance of intermediate methylation levels observed in trophoblast stem cells. doi.org/10.1038/s41556…

🧬 The placenta's DNA is strange: its methylation patterns are scattered throughout. This is the result of two enzymes that normally work in their respective pens but compete in the placenta, as Sara Hetzel Raha Weigert show in Nature Cell Biology. #Meissner Lab molgen.mpg.de/4621109/news_p…

1/2 The presence of extraembryonic cells in the developing gut has long puzzled scientists. Julia Batki (l) and Sara Hetzel (r) (#Meissner lab) now gained new insight into the fate and molecular characteristics of these cells. Nature Cell Biology Read more: molgen.mpg.de/4717564/