Mind-blowing work from Nan Hao Lab about aging! Yeast cells takes two alternative (!!!) aging paths- mitochondrial deterioration or genome instability. A lot to digest what this means for a multiple cellular system, when cells are specialized for mitochondrial or genome maintenance

Fascinating study in yeast showing "aging to be more of a programmable decision process rather than a simple accumulation of deleterious events". Science Magazine

This is a fantastic example of '#Aging as programmatic decoherence', which IMO is the best model for what aging means at both cell, tissue and organism level. #iPS rejuvenation is another great example. Anyway congratulations Nan Hao Lab, looking forward to more work on this!

New from Nan Hao Lab in Science Magazine today and as covered by Emma Betuel: “His team created a third pathway that allowed cells to live twice as long compared to the other two aging pathways.“ inverse.com/mind-body/agin…

Elegant study of aging as a cell fate decision...

A beautiful work that combines single cell imaging and mathematical analysis to reveal new insight about aging ! Congrats Nan Hao Lab

Scientists at the University of California San Diego may be one step closer to being able to delay the aging process. cnn.it/2OMe5RC

Congrats Nan and colleagues Nan Hao Lab! Not often I encounter a new study on metabolism and epigenetics @cnn. Looking to forward to reading the paper soon - sounds interesting. cnn.it/2OMe5RC

We are hiring! Post-docs and/or staff scientists to work on exciting projects related to oxygen and vitamins. Combination of systems biology, in vivo physiology, cell metabolism and more...Email [email protected] if interested. More details at ishajainlab.com. Please RT!

CD3e improves CAR-T signaling and anti-tumor function Cell! Great to be part of this amazing collaboration with Chenqi Xu and Catherine Wu etc. Congrats to Takeya Masubuchi fellow of HFSP and the team! cell.com/cell/fulltext/…

Glad to share our paper on antiviral interferon response published at eLife. Cell cycle gating provides a temporal compartmentalization of feedback loops, enabling signal duration-dependent priming vs desensitization. First mammalian cell paper in lab! doi.org/10.7554/eLife.…

Immune environment is dynamic and complex. Super interesting work shows the same type I interferon activates positive or negative feedback to prime or sensitize interferon response based on signaling duration. Congratulations to Nan Hao Lab! What an adventure from yeast to immunity!

Out today in Nature Chemical Biology we’re excited to introduce our new ultrasensitive PKA sensor for in vivo imaging, ExRai-AKAR2! Many thanks to our wonderful team of collaborators! (1/2) nature.com/articles/s4158…

Our first review paper is out: onlinelibrary.wiley.com/doi/full/10.10… Viraat reviewed chromosome conformation capture techniques, their historical development and the biological insights obtained Specific focus on Micro-C and how it can reveal transcriptional interactions largely absent in Hi-C

Awesome painting from artist and former lab manager Peter Arvidson PeterArvidson.com highlights the awesome work co-authored by former labmate Chris Chidley! Beautiful art and beautiful science 👏👏👏 Congratulations to all!

Come and join us! We are looking to hire a Technical Associate (Research Assistant) to start summer 2021 for a joint project with Fei Chen MIT Dept of BE Broad Institute More info: ashansenlab.com/join.html Apply: careers.peopleclick.com/careerscp/clie… Feel free to get in touch with any questions.

Please help RT! Zhou lab at Boston Children's and Harvard Medical School is looking for a Research Assistant / lab tech, to help us study how immune cells talk to other cell types and their microenvironment. Please apply here sjobs.brassring.com/TGnewUI/Search…

Our attempt to summarize typical strategies (by many labs) to make circuits more stable.

Happy to share our new work on engineering a gene clock to slow cell aging, published in Science today! science.org/doi/10.1126/sc…

Happy to share our recent review on design principles of gene circuits for longevity! sciencedirect.com/science/articl…