Our new publication was featured in this week's issue of NEJM with an editorial. We attempt to address the limitations of the MOTHER trial and compared the risks of adverse neonatal and maternal outcomes between maternal buprenorphine and methadone use: nejm.org/doi/full/10.10…

Check out our monthly literature scan covering perinatal and pediatric pharmacoepidemiology papers for the month of October 2022. harvardpreg.org/literaturesear…

Congrats to Program On Regulation, Therapeutics, And Law Harvard Perinatal & Pediatric Pharmacoepidemiology CEE student Liz Nyamwange for being a top 300 scholar in the Society for Science #RegeneronSTS Regeneron Science Talent Search for her work revealing disparities in adherence to hypertensive meds in pregnancy! societyforscience.org/press-release/…

New paper from our #InPreSS collaboration on antipsychotic safety in pregnancy. 🤗

If you are interested in joining our group, please do not hesitate to reach out!

Observational studies are often the only option to estimate effects of interventions during #pregnancy. Thinking of emulating a #TargetTrial during pregnancy using healthcare databases? Here we review challenges and propose solutions to common biases👇 pubmed.ncbi.nlm.nih.gov/36722806/

Check out the call for papers in the special series on Pediatric and Perinatal Pharmaco-epidemiology @PPE_journal. Dr. Sonia Hernandez-Diaz will be one of the guest editors for this series (Submission deadline: Saturday, 1 April 2023). onlinelibrary.wiley.com/page/journal/1…

Check out our monthly literature scan covering perinatal and pediatric pharmacoepidemiology papers from the months of November and December 2022! harvardpreg.org/literaturesear…

We are holding a Symposium at the Harvard TH Chan School of Public Health on 12/15 1-4pm, co-sponsored by CAUSALab and Harvard Perinatal & Pediatric Pharmacoepidemiology . Welcome to join us by registering for free and attending in person or via Zoom!

It's happening - the Kolokotrones Symposium on Causal Inference in Pregnancy started with Dr. Sonia Hernadez-Diaz explaining "Why is Causal Inference Harder During Pregnancy." CAUSALab

Dr. Anne Lyerly Anne Drapkin Lyerly from UNC Bioethics continued the introduction by highlighting the "pregnancy paradox" - challenges that we encounter in including pregnant people in randomized trials.

The 16th #KolokotronesSymposium is officially underway! CAUSALab's Prof. Sonia Hernandez-Diaz, Co-Director of Harvard Perinatal & Pediatric Pharmacoepidemiology welcomed everyone and kicked off the day with a presentation on "Why is #CausalInference harder during #pregnancy?"

Dr. Lyerly Anne Drapkin Lyerly ended her presentation with a thought-provoking quote from Dr. Frances Kelsey who saved the U.S. from the thalidomide catastrophe in the 1960s, which illustrates the importance of #CausalInference research in #Pregnancy. UNC Bioethics

#KolokotronesSymposium #pregnancy Dr. Leyla Sahin from U.S. FDA shared her view on the regulation of treatments during pregnancy. Research using large healthcare data is taking an increasingly important role in providing real-world evidence on medication in pregnancy. CAUSALab

Dr. Rasmussen in her presentation went through the regulatory efforts over the decades aimed at the prevention of birth defects due to isotretinoin.

Dr. Cohen concluded his talk by emphasizing how high-quality data from large healthcare datasets can be integrated with high-quality data from registries. @WmnMentalHealth

The last presenter of 16th #KolokotronesSymposium, Dr. Krista Huybrechts, co-director of Harvard Perinatal & Pediatric Pharmacoepidemiology, demonstrated how to conduct a study in large healthcare databases using the evaluation of buprenorphine vs. methadone in #pregnancy recently published in NEJM as a case study.

Dr. Huybrechts further concluded that research on medication use in #pregnancy "is not simply a yes/no question. It is about establishing the level of risk and discussing whether it is acceptable given the benefits, (other) risks, and costs."

Today's #KolokotronesSymposium ended with a panel discussion, moderated by Dr. Brian Bateman. A sincere thank you to everyone who joined us in person and over Zoom! Inspired by the talks and audiences' questions, we will continue our research on #CausalInference in #pregnancy!