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Absolutely over the moon about this Focus issue on the future of bioimage analysis!!! (a short thread)

Very sad news on the passing of Professor Rohini Godbole. Full of energy and drive, she was physicist, flag-bearer for women in science, public citizen, and friend to many. She will be much missed and is irreplaceable.

It's my pleasure to present the next big preprint from SheqLab! An exciting application of our O-MAP platform that I hope will transform the study of nuclear architecture. If you've ever wanted to dissect the subnuclear "neighborhood" around an individual locus, read on! (1/30)

"We are not making science for science. We are making science for the benefit of humanity." This #WorldAidsDay we highlight Françoise Barré-Sinoussi, awarded the 2008 Nobel Prize in Physiology or Medicine for her role in the discovery of human immunodeficiency (HIV) virus.

Check out this event. Hope to see you there! thescicommsynapse.in/event-details/…

18th @ 18!

Turtles do win the race! 🐢 🔥 Coming in hot at #5 is a study from Drs. Christopher Zdyrski and Nicole Valenzuela, in which they developed turtle liver organoids as a model to decode the organism's unique adaptations. x.com/organoidscienc…

Ending 2024 in style! We found that LINE1s are key “architects” of the nucleolar genome in human embryonic stem cells. This work brings together 2 facets of Barbara McClintock’s pioneering work: nucleolar organizer regions and transposable elements. genesdev.org/cgi/doi/10.1...

#HMPvirus is nothing to panic about. It’s a known virus that causes respiratory infections, mostly mild. Rather than jump at detection of every pathogen, we shld all take normal precautions when we have a cold: wear a mask, wash hands, avoid crowds, consult Dr if severe symptoms

Using single-cell RNA-seq + PBAT, we characterised the molecular profiles of NSN and SN GV oocytes, which show highly distinct chromatin structures (example below). A great collaboration!

Ghee is not butter, I need to clarify it for some of you

This is so good

How does the brain respond to art? In a new PNASNews study, by showing paintings to people while scanning their brains, @dshohamy Celia Durkin & colleagues shed light on this question. Read: zuckermaninstitute.columbia.edu/art-brain-beho… @columbia @UMnews #neuroscience #art

India enters the global Longevity race! GOQii Sanjeevini is among the Top 40 teams worldwide in the $101M @XPRIZE Healthspan—and the only one from India. From Ayurveda to AI, we’re on a mission to redefine aging and lead the world in healthy living. Watch the vision.

A baby named KJ, who was born with a rare genetic disorder – CPS1 deficiency – is healed thanks to doctors at the Children's Hospital who administered the world’s first personalized gene-editing treatment. The research team used base editing, a gene-editing method invented by HHMI

This week's genome editing triumph is a big deal. Here's why erictopol.substack.com/p/the-first-hu…

Very excited to share our latest work in Molecular Cell showing NPM1 stabilizing the association of nucleolus associated domains (NADs) and recruiting G9a to establish their repressive chromatin states. sciencedirect.com/science/articl…

Are you curious about how genomic domains associate with the nucleolus? Check out the latest study from RaffaellaSantoroLab in Molecular Cell. cell.com/molecular-cell…

New method drop: HCR-Proxy, a modular proximity labelling approach to profile local proteome composition around RNA at nanoscale subcompartmental resolution. We resolved nested nucleolar layers and uncovered the grammar of spatial protein partitioning. shorturl.at/OdUdH

Integration metrics for evaluating batch effects on single cell atlases could be hacked! Hanchen Wang and Aviv picked this up and proposed new metrics! Very interesting read