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Have you entered our imaging contest yet? Details here: nif.hms.harvard.edu/news/236 - Check out this image from our previous contest. By Swathi Ayloo The Gu Lab #VS120 Slide Scanner The image is a snapshot of blood vessels in the cerebellum of a 10 day old mouse.

Technical Report| The Gu Lab DevermanLab identify an #AAV variant (AAV-BI30) with high specificity and efficacy for transduction of #endothelial cells across the #CentralNervousSystem. Broad Institute nature.com/articles/s4416… 👉rdcu.be/cLmoT

alleninstitute.org/what-we-do/fro…

Plasmids to generate AAV-BI30, our vector that can specifically manipulate CNS endothelial cells, can be found on Addgene: addgene.org/browse/article…

We had a lot of fun writing this Neuron N&V in Neuron on exciting new story from The Gu Lab. identifying a new way for pericytes to suppress BBB transcytosis. Open access Neuron authors.elsevier.com/a/1f5cb3BtfH1Y…

Farewell happy hour yesterday for our lab manager Chris - we’ll miss you! + congrats to our former postdoc, Swathi, and Chris for their recent paper🎉

New lab photo + behind the scenes 📸

#microscopymonday image by Xavier J. du Maine, PhD, The Gu Lab using our #VS120 slide scanner Here is the mouse choroid plexus, a structure in the brain ventricles that produces a clear fluid called CSF that helps to protect the brain and clear waste from it. The choroid plexus consists...

#FluorescenceFriday image by @urs_langen, The Gu Lab Harvard Medical School - red blood cells (green) in brain capillary (red) Image was acquired on a Leica Microsystems #SP8 confocal and processed using Imaris 3D/4D Imaging

Happy #FluorescenceFriday Image by @urs_langen, The Gu Lab of astrocytes (green, GFAP) in median eminence in touch with blood vessels (red, CD31) Image was acquired on a Leica Microsystems #SP8 confocal and processed using Imaris 3D/4D Imaging

Humbled to participate in this scientific statement - I learned so much! The Neurovasculome: Key Roles in Brain Health and Cognitive Impairment: A Scientific Statement From the AHA/ASA tinyurl.com/3er68bh5

A new scientific statement examines the neurovasculome, shedding light on the relationship between the brain & its vessels and its roles in cognitive function. ✍️ costantino iadecola The Gu Lab Anusha Mishra Sanjay Misra MD, FSIR, FAHA, FACR @SusanneVanVeluw 📍 Stroke AHA/ASA: spr.ly/6012OzV64

Out in press! With Andy Shih Rodrigo Constantino Anusha Mishra Anusha Mishra @SusanneVanVeluw Rodrigo Constantino spr.ly/6012OzV64

Researchers Uncover Signal Needed for Blood-Brain Barrier HMS News article on new research from Sean Megason, @gulabneuro, Allon M. Klein, and colleagues, first author @NatashaOBrown1 hms.harvard.edu/news/researche…

Congratulations to our newly minted Dr. Hannah Zucker!

New paper out in Nature Neuroscience! nature.com/articles/s4159…