Des scientifiques de l’#UNIGE ont identifié les séquences génétiques régulant l’activité des gènes responsables de la croissance osseuse. Guillaume Andrey Fabrice Darbellay #science #médecine #recherche #génétique ow.ly/cfek50SizmR

Fine tuning the cellular abundance of each subunit of the SWI/SNF complex is essential for the adequate opening of #enhancers and #promoters. Beautiful work from our next door colleagues.

🎉🎉🎉New preprint alert! 🎉🎉🎉 We present our deconstructed approach to studying limb development and regeneration-related cell types. biorxiv.org/content/10.110… Here is a short 🧵:

The Kvon lab is hiring a postdoc. We developed lots of powerful in vivo tools to address exciting questions in gene regulation, congenital disorders and evo-devo. We are located in sunny Southern California close to the ocean. Email me if interested. kvonlab.org

We are looking for a bioinformatician Collège de France CIRB_CdF in Paris to analyse genomic/epigenetic datasets🧬 in the context of a synergy European Research Council (ERC) long term program. See below and apply😎 RT🙏

So happy that our preprint is finally out! If you're interested in the advantages of long-read direct RNA sequencing in population studies, this is for you.

I am so excited to share this part of my PhD where we tackle the question: What impact do 3D contacts have on how enhancers regulate their target genes? biorxiv.org/content/10.110… 1/

Hoxb13 and the control of body length, with #gastruloids to the rescue and #CTCF as heterochronic factors🕰️now in bioRxiv biorxiv.org/cgi/content/sh…🤘A long-lasting project with many colleagues to thank🙏and congratulate!👏 the Node CTCF Papers 📚

Super happy to get my first Spanish national grant!!! Plus one extra PhD contract! 🥳🥳🥳 Reach out to me if you want to join the lab to work on the genetic evolution of moles using synthetic genomic approaches 😉

We present The Transcription Factor Binding Landscape of Mouse Development🐭🧬 #DevBio We use CUT&RUN-LoV-U to map Many SignalingPathways X 4tissue X 2stages It is a huge dataset - yet only the beginning of the TranscriptionFactorBinding(TFB)-OMICS biorxiv.org/content/10.110…

I'm excited to share this collaborative work with Katerina Kraft and Matt Jones that started as an exploration of the nuclear organization of ecDNA in colon cancer cells and ended with some neat findings on repetitive elements. See thread for more!

🚨Preprint alert🚨 Excited to share the #preprint version of our work MundlosLab ! Curious about how a transposable element (TE) insertion can cause developmental phenotypes? 🧬🦠🐁 Check the 🧵 below and the full version on BiorXiv: biorxiv.org/content/10.110…

🚨#JobAlert🚨 Join us in Geneva UNIGE_en! We have an open #postdoc position starting in 2025. If you are interested in studying chromatin regulation and working with brain organoids, apply now! #sciencejobs More info: unige.ch/medecine/gede/…

First preprint from the lab 🚨 How can enhancers regulate target promoters across vast genomic distances, and what is the role of cohesin loop extrusion in the process? biorxiv.org/content/10.110… (1)

It's a great pleasure that our study about the regulatory role of the Shox2 gene desert – a non-coding genomic region with multiple critical functions in embryogenesis - is finally out! #unibern #UCalgary #BerkeleyLab nature.com/articles/s4146… #devbio #enhancers #Shox2 #GeneDeserts

I'm very excited to share that I’ve started as a group leader Karolinska Institutet. I am looking for curious, enthusiastic and collaborative postdocs and assistants (pre-PhD) to join us to decipher regulation of hypoxia cell states that govern systems oxygen homeostasis 1/3

Very excited to share our latest work in Nature Communications where we identify two limb mesenchymal progenitor populations involved in congenital and evolutionary digit variation. Congratulations to all authors involved, it’s been such a good team work. nature.com/articles/s4146…

Studying the effect of mutations in embryos without ignoring the questions raised by animal experimentation. Interview with 👨‍🔬 Guillaume Andrey, who is dedicated to understanding the genome as best he can with the fewest possible mice. Université de Genève horizons-mag.ch/2025/03/06/exc…

Our work bridging enhancer-promoter proximity to phenotypic outcomes in vivo is out! Shout out to Olimpia Bompadre, to Marie Kmita's lab, and to all the co-authors. nature.com/articles/s4146…