Looking for post docs. If you are interested in what we do, and in potentially moving to NYC…please reach out!

Amazing place to be!!

Very excited to share our latest work on the uncoupling of epithelial regeneration and tumorigenesis in the gut! nature.com/articles/s4158…

End-of-the-year preprint 🧵! Ever wondered how a cancer driven by a single mutant oncogene becomes molecularly & cellularly heterogeneous? Why metastases share drivers w/primary tumors but are more aggressive?

The science of pasta cacio e pepe 🇮🇹👨‍🍳 "Finally, we present a scientifically optimized recipe based on our findings, enabling a consistently flawless execution of this classic dish." Applied science at its best, with real-world impact arxiv.org/abs/2501.00536

Fantastic #PhD opportunity in #DataScience at SISSA in #Triest, #Italy. Applications from #Bioinformatics to #cosmology and #Neuroscience. Deadline Feb14! datascience.sissa.it/how-to-apply

It's out! If you look for a reliable reporter system for your Nucleic Acid Therapeutics needs, we got you covered! The NATURA system is available to the community on Addgene. Congrats to Tommaso Tabaglio for leading this incredible effort! sciencedirect.com/science/articl…

Amazing to see this out. A mechanistic study with deep implications for future clinical work. Cannot be prouder ⁦Slim Mzoughi⁩ A huge thanks to all our collaborators ⁦Gaetano Gargiulo & ggargiul.bsky.social⁩ @nickbar36316207 ⁦Owen Sansom 🏳️‍🌈⁩ ⁦NIH Funding⁩ nature.com/articles/s4158…

What an amazing cover! Congrats ⁦gloglita⁩!!

The AACR is deeply concerned that the Administration’s recent actions are threatening NIH and its mission to accelerate progress for patients with cancer and other diseases that afflict millions of Americans. We urge Congress to restore stability to NIH: brnw.ch/21wQMO3

csr.nih.gov/RevPanelsAndDa… link to check whether any study section is still happening. If NIH cannot post the study section on the national register then it cannot formally happen. The ripple effects can be devastating if no new funding is awarded.

Exciting tech advance 4 cancer research: FFPE-CUTAC enables phenotype queries from archived FFPE tissues. This finds a striking correlation between hypertranscription of histones (but not ribosomal genes) & chromosome arm losses, hence, cancer evolution. science.org/doi/10.1126/sc…

"More than 99% of new drug approvals (2010-2019) were funded by NIH. Why dismantle the engine that made the U.S. a world leader in innovation and drug development ? #DoNotDefundScience jamanetwork.com/journals/jama-…

New in nature: Human-correlated genetic models identify precision therapy for liver cancer rdcu.be/ebdH2 Josep Llovet and team Icahn School of Medicine at Mount Sinai validated the molecular profiles of preclinical models against human HCC data. #livercancer #HCC

Myeloid Cell Checkpoints: Ido Amit, Florent Ginhoux, and Miriam Merad addressed this topic in a symposium at the inaugural AACR IO Conference on Discovery and Innovation in Cancer Immunology. #AACRIO25 IdoAmitLab @realFlorentGinhoux Miriam Merad, MD, PhD

Now more than ever the message is: this research can soon have an impact on people’s lives. Do not defund science!Proud of this collab with 大石公寿 and the whole #RNA modulation for therapeutics Lab (kudos to JinRong in particular!) journal-of-hepatology.eu/article/S0168-…

Here we characterize PRDM10 as an essential maternal transcription factor and dissect its role in regulating oocyte maturarion and oocyte-to-embryo transition! On to the next! Congrats to Daniel M. M. the true mastermind behind this work! nature.com/articles/s4146…

Strong article from Tom Maniatis, head of the NY Genome Center, on the history of the NIH and its role in maintaining U.S. scientific leadership. Safeguarding the future of biomedical science in the United States: Cell cell.com/cell/fulltext/…

Awesome opportunity

Excellent article that highlights the contribution of NIH grant funding to fueling economic activity. An important read especially for non- scientist to understand how disruptive NIH cuts are both to medicine and to the economy.