#BTCSummit23 is a wrap! Thanks to all who attended in person and virtually last week, including TeamLab members, speakers, and special guests. #RadicalCollaboration

KRAS Resistance, Mechanisms, and Therapeutics: Andrew Aguirre, Kenneth P. Olive, and Mallika Singh will address this topic in a plenary session at the AACR Conference on Advances in Pancreatic Cancer Research (Sept 15-18, Boston). bit.ly/4el6lAu #AACRpan24 KenOliveLab

BIG KRAS day today at Cancer Discovery!! First study led by Andrew Aguirre Dilly Julien and colleagues at Hale Family Center For Pancreatic Cancer Research MD Anderson Cancer Center Memorial Sloan Kettering Cancer Center Koch Institute at MIT Mechanisms of resistance to oncogenic KRAS inhibition in #PancreaticCancer aacrjournals.org/cancerdiscover… In this study

Exciting findings from the Hale Center Dana-Farber have just been published in Cancer Discovery. The collaborative study, led by Andrew Aguirre, Stephanie Dougan and colleagues, characterized resistance to oncogenic #KRAS inhibition in #PancreaticCancer.

Great National Cancer Institute blog post on the recent back-to-back Cancer Discovery papers from the labs of Andrew Aguirre and Tuomas Tammela about the classical cell state driving resistance to KRAS inhibition in pancreatic cancer: cancer.gov/news-events/ca… Dana-Farber Memorial Sloan Kettering Cancer Center

Fantastic Rising Star Keynote by Joe Mancias Mancias Lab at #AACRpan24 highlighting the role of autophagy in PDAC. Hale Family Center For Pancreatic Cancer Research

Apparently getting a lightning talk at #aacrpan24 is harder than getting an R01 so congrats to Hale Family Center For Pancreatic Cancer Research member Brandon Huffman, MD!

Amazing back-to-back talks by our own Cathy C Garcia and Christian F. Ruiz at #AACRPan24 on mechanisms of obesity-driven #PancreaticCancer in the cachexia, diet, and metabolism session! Yale Cancer Center Yale Department of Genetics Yale Cancer Biology Institute Lustgarten Foundation

Gurcan Gunaydin, a talented postdoc in the Freed-Pastor lab Hale Family Center For Pancreatic Cancer Research, presenting his work on the discovery and therapeutic potential of novel cryptic peptides in #PDAC #aacrpan24

All the KRAS inhibitor compounds Andrew Aguirre could fit on a slide! #AACRPan24

I found these three summary slides from Channing Der on (left) diverse mechanisms of action for KRAS inhibitors & (center, right) acquired genetic mechanisms of resistance to KRASi really useful. #AACRPan24

If the pair of plenary sessions at #AACRPan24 on #KRAS piqued your interest, be sure to check out the In Focus article in Cancer Research by Andrew Aguirre Ben Stanger & Anirban Maitra on KRAS inhibition as a treatment paradigm for pancreatic cancer patients. aacrjournals.org/cancerres/arti…

#AACRpan24 co-chair and Hale Family Center For Pancreatic Cancer Research PI Stephanie Dougan was acknowledged this morning for her work on the AACR organizing committee

Another amazing Hale Family Center For Pancreatic Cancer Research study presented at #AACRPan24! Check out the paper that just came out on Monday doi.org/10.1158/1078-0…

Targeting resistance to RAS inhibition in pancreatic cancer: Dana-Farber's Andrew Aguirre presents in an #AACR25 session exploring advances in KRAS biology that may provide new therapeutic options for #PancreaticCancer. ➡️ bit.ly/4cYt3hx

If you're attending the #AACR25 session on Advances in #KRAS Biology in PDAC don't miss this important Cancer Discovery paper on mechanisms of resistance to oncogenic KRAS inhibition in pancreatic cancer by session speaker Andrew Aguirre doi.org/10.1158/2159-8…

Check out Yi Wen Kong’s fantastic work at #AACR25