🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

This was a fun collaboration with @blairperry614 Daren Card, Ph.D. Giulia Pasquesi Aundrea Westfall, Steve Mackessy, and Todd Castoe. It felt a little like 'getting the band back together', since Blair, Daren, Giulia, and I were once all grad students in the Castoe Lab together.

PI and first author reading the reviews

It's been online since last year, but happy 2 announce recent publication in Frontiers focused on illuminating the #squamate #MHC! Many thanks to co-authors Andrew Van Camp, Trent Santonastaso, Mike Jensen-Seaman, Nicola Anthony, & Scott V Edwards. doi.org/10.3389/fgene.… 1/12

Absolute legend.

t-SNE is amazing

Vingeglue is back 🤍⚔️💛 #TdF2023

#FreeGanna 🥳

💥Excited to unleash ENCOTE: Encyclopedia of Transposable Elements with cis-regulatory activity in the human genome! Collab w Ting Wang for #ENCODE led by🔥trio Alan Du, Jason Chobirko & Xiaoyu Zhuo TEs = 25% of all cCREs = 200,000+ elements!! Deep dive! 1/n biorxiv.org/content/10.110…

Ops! TEs did it again!!! (and again and again). This time, it's an endogenous thermostat of primate inflammatory and innate immune response.

Our work on a LINE-1-derived enhancer of IFNAR1 is out in Mobile DNA , led by the first PhD graduate from my lab Carmen Buttler!

Best news ever. If true

Predicting Alu exonization in the human genome with a deep learning model biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

Preprint alert! Do you like retrotransposons 🧬? Do you like squamates 🦎🐍? Do you like TEs/retrotransposons in squamates? Dr. Simone Gable studied CR1 retrotransposons across ~350 amniote genomes, revealing dynamic patterns of genome evolution in reptiles! biorxiv.org/content/10.110…

Proud to share the first neuronal model of the disease we discovered in 2017! Here we describe that #YY1 mutations affect corticogenesis in a cell-type specific fashion, and in #organoids, we observed a phenotype that recapitulates clinical features!

💥Our new preprint! Transposon ADDICTION in development! Gag proteins of endogenous retroviruses are required for zebrafish development Study led heroically by Sylvia Ni & Jonathan Wells This work has transformed my view of transposons, no less! 🧵1/n biorxiv.org/content/10.110…

Another big shout out to the organizers, speakers, presenters and everyone that attended Cold Spring Harbor Laboratory #bog24 for the amazing conference!

Stranger Genes! The one & only Edward Chuong on immune splicing regulation mediated by TEs - beautiful work led by Giulia Pasquesi (Giulia is now in the faculty job market!) #cshlTE24 biorxiv.org/content/10.110…

He was the worst President in history. And when he got voted out, he tried to stage a coup. Then he stole national secrets and sold the ones he didn't store in the bathroom. He was convicted of fraud, found liable of sexual assault and convicted of 34 felonies. He is half a

A story of transposons, innate immunity, and how human (and primates) possess an endogenous system to tune interferon response through the relative expression level of a signaling receptor and its alternatively spliced decoy.

I don't use this platform much anymore, but I'm happy to share our work on sexual selection and the genomics of speciation in barn swallows. Thanks for reading and sharing, if of interest! science.org/doi/10.1126/sc…